<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:f22cd5bf-3bf0-4da1-b4d1-5c54d63872e6,g:57686fdd-32fd-4aa1-80d7-c3647b458cf4-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CoverPage" xlink:type="simple" xlink:href="tndm-20210630.xsd#CoverPage"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_43774f9f-e4b9-4213-8bda-8feaf3c0cdbb" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_DocumentType_43774f9f-e4b9-4213-8bda-8feaf3c0cdbb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_4c1ea7f7-1138-43bc-a020-9fc2bd14190e" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_DocumentQuarterlyReport_4c1ea7f7-1138-43bc-a020-9fc2bd14190e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_d3ef6c4d-51c1-455f-8cce-8c5d50d2c805" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_DocumentPeriodEndDate_d3ef6c4d-51c1-455f-8cce-8c5d50d2c805" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_d15c4b64-a1b9-4321-9ec2-80030a89d0f5" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_DocumentTransitionReport_d15c4b64-a1b9-4321-9ec2-80030a89d0f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_d34a3f26-5756-4415-bc90-06c2a0b94a2d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityFileNumber_d34a3f26-5756-4415-bc90-06c2a0b94a2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_10e4fce4-60e9-4d26-a87c-c9630068f0d9" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityRegistrantName_10e4fce4-60e9-4d26-a87c-c9630068f0d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_1e80f70c-7c0b-49bf-b855-35b1c20c9b1d" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityIncorporationStateCountryCode_1e80f70c-7c0b-49bf-b855-35b1c20c9b1d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_66514bd9-1d95-4c53-be3a-3bff261f8401" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityTaxIdentificationNumber_66514bd9-1d95-4c53-be3a-3bff261f8401" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_73de4468-8374-49a7-85e2-6862c6822445" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityAddressAddressLine1_73de4468-8374-49a7-85e2-6862c6822445" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_efe22b39-fb9f-44ba-8cee-af6f30953af9" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityAddressPostalZipCode_efe22b39-fb9f-44ba-8cee-af6f30953af9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_85083b88-8364-4df8-a920-63d4e998a7d1" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityAddressCityOrTown_85083b88-8364-4df8-a920-63d4e998a7d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_c5534cfd-ce54-4676-a797-32cbe27c935b" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityAddressStateOrProvince_c5534cfd-ce54-4676-a797-32cbe27c935b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_fbca9c2a-6214-4c43-9904-3476fa5bbc21" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_CityAreaCode_fbca9c2a-6214-4c43-9904-3476fa5bbc21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_db9445f0-4a07-45d7-b006-97f356914b82" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_LocalPhoneNumber_db9445f0-4a07-45d7-b006-97f356914b82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_ddb60261-ebd7-4b19-a886-b9514856b3ab" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_Security12bTitle_ddb60261-ebd7-4b19-a886-b9514856b3ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_1321a5b5-4737-485b-b480-957b2f674f92" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_TradingSymbol_1321a5b5-4737-485b-b480-957b2f674f92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_3f1c634b-16fc-4ef5-966e-66dac9e2a68a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_SecurityExchangeName"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_SecurityExchangeName_3f1c634b-16fc-4ef5-966e-66dac9e2a68a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_37076118-057d-422c-9287-9107d2bd2679" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityCurrentReportingStatus_37076118-057d-422c-9287-9107d2bd2679" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_c4c34fa4-a9af-445a-b7f8-689564baa038" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityInteractiveDataCurrent_c4c34fa4-a9af-445a-b7f8-689564baa038" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_8a246200-5d48-4fb5-836e-6db8d576431a" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityFilerCategory_8a246200-5d48-4fb5-836e-6db8d576431a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_fd0b5274-eebb-4dd6-babf-a83f5ab40ce0" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntitySmallBusiness_fd0b5274-eebb-4dd6-babf-a83f5ab40ce0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_70129ff5-4fed-4619-a544-30d32e12de59" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityEmergingGrowthCompany_70129ff5-4fed-4619-a544-30d32e12de59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_f46af4f9-625a-4604-844b-96d7d6419a03" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityShellCompany_f46af4f9-625a-4604-844b-96d7d6419a03" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_8c0ec60d-c6eb-4f8b-aca5-dd252126c5e6" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_8c0ec60d-c6eb-4f8b-aca5-dd252126c5e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_33d61f5c-ae38-4fb4-ac79-f85dbb030a54" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_AmendmentFlag_33d61f5c-ae38-4fb4-ac79-f85dbb030a54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_36b306b9-766b-417a-9216-b3430c45e691" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_DocumentFiscalYearFocus_36b306b9-766b-417a-9216-b3430c45e691" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_43264699-e31b-4991-a524-437340861e93" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_DocumentFiscalPeriodFocus_43264699-e31b-4991-a524-437340861e93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_ae49b36d-ef51-4680-9545-e0c00ff29067" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_EntityCentralIndexKey_ae49b36d-ef51-4680-9545-e0c00ff29067" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_3cf1eead-7350-4447-b49e-6d1d070b1046" xlink:href="https://xbrl.sec.gov/dei/2021/dei-2021.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="29" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_8e6d1cdd-8371-4cd6-b26b-01128df563a2" xlink:to="loc_dei_CurrentFiscalYearEndDate_3cf1eead-7350-4447-b49e-6d1d070b1046" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETS" xlink:type="simple" xlink:href="tndm-20210630.xsd#CONDENSEDCONSOLIDATEDBALANCESHEETS"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_e7827eac-25e3-4d92-926d-fd94ef138c12" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_e7827eac-25e3-4d92-926d-fd94ef138c12" xlink:to="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:to="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_9a48829c-5dda-4d3d-95bc-6ae5c8964ae2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_9a48829c-5dda-4d3d-95bc-6ae5c8964ae2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermInvestments_7c82363c-ac7c-4902-b951-9b377b99ca24" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShortTermInvestments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:to="loc_us-gaap_ShortTermInvestments_7c82363c-ac7c-4902-b951-9b377b99ca24" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_fdb9c3ac-47bd-4068-84d7-718e461bfb68" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_fdb9c3ac-47bd-4068-84d7-718e461bfb68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_f70f7dd3-56da-4cdc-9e31-d738ef1dd088" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:to="loc_us-gaap_InventoryNet_f70f7dd3-56da-4cdc-9e31-d738ef1dd088" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_d6a26045-b6b7-41e5-9e23-411ea22d354f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_d6a26045-b6b7-41e5-9e23-411ea22d354f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_ea863d71-3fda-4530-aca6-080e17b1002d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_653077f0-e632-41a9-aa9b-b99b3b287202" xlink:to="loc_us-gaap_AssetsCurrent_ea863d71-3fda-4530-aca6-080e17b1002d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_103c2e82-dd4f-4fb8-98b6-66bff1c7ba38" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_103c2e82-dd4f-4fb8-98b6-66bff1c7ba38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_4069fc48-6ab5-49cb-ab87-f8b37a8438fc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_4069fc48-6ab5-49cb-ab87-f8b37a8438fc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_d589a438-0a14-469e-8891-99cfd284e02b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_d589a438-0a14-469e-8891-99cfd284e02b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_8ca33f6b-7fca-4d24-9bf4-fbad50d67b89" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Assets"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_1733f2b4-42eb-4234-8475-11d49c8e8944" xlink:to="loc_us-gaap_Assets_8ca33f6b-7fca-4d24-9bf4-fbad50d67b89" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_e7827eac-25e3-4d92-926d-fd94ef138c12" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_b48f69bf-aef6-4c4a-9b6c-dda3c6a3956a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_AccountsPayableCurrent_b48f69bf-aef6-4c4a-9b6c-dda3c6a3956a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_9a834a77-6a7b-4544-858d-d9e1afb70fb4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_9a834a77-6a7b-4544-858d-d9e1afb70fb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_8f3640a5-f442-49d8-8412-2d5177486b35" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_8f3640a5-f442-49d8-8412-2d5177486b35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_c830e0e2-f577-4b96-9a0e-13b387b85fd8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_c830e0e2-f577-4b96-9a0e-13b387b85fd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CommonStockWarrants_8d775328-9eb3-4536-9ff1-5c9cdcf35557" xlink:href="tndm-20210630.xsd#tndm_CommonStockWarrants"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_tndm_CommonStockWarrants_8d775328-9eb3-4536-9ff1-5c9cdcf35557" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_668f9206-8936-45bb-8aaf-bb16e143f94b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_668f9206-8936-45bb-8aaf-bb16e143f94b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesCurrent_d62190dc-a706-493e-9fae-6a4d5d927b9d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLiabilitiesCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_OtherLiabilitiesCurrent_d62190dc-a706-493e-9fae-6a4d5d927b9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_6b1a2b01-6011-4a06-acff-b65e9cc6d0be" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_42daacb8-3a37-44a1-8cc7-0cce226ea50d" xlink:to="loc_us-gaap_LiabilitiesCurrent_6b1a2b01-6011-4a06-acff-b65e9cc6d0be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_2c24c0a1-9d93-47bf-914a-2fa19ce42e38" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_2c24c0a1-9d93-47bf-914a-2fa19ce42e38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_ef797168-1c65-4c6c-8873-bb088f1a60f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_ef797168-1c65-4c6c-8873-bb088f1a60f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_3184b6e5-b2cc-43df-9ea1-3ef769b8b87c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_3184b6e5-b2cc-43df-9ea1-3ef769b8b87c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_58392736-ad48-4167-9c47-adab7f26aa49" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_Liabilities_58392736-ad48-4167-9c47-adab7f26aa49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_3a46007c-b412-44b7-8c1e-a9aab30d9d6a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_CommitmentsAndContingencies_3a46007c-b412-44b7-8c1e-a9aab30d9d6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_604cc4e6-2acc-46a8-befe-e08432bc29cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:to="loc_us-gaap_CommonStockValue_604cc4e6-2acc-46a8-befe-e08432bc29cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalCommonStock_80695892-fcfd-4b1d-a2cd-e5d1d7c396bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapitalCommonStock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:to="loc_us-gaap_AdditionalPaidInCapitalCommonStock_80695892-fcfd-4b1d-a2cd-e5d1d7c396bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_b7a2fbe7-5533-43a0-8a8a-0139fd10a6c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_b7a2fbe7-5533-43a0-8a8a-0139fd10a6c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_be28e56d-5640-4bc1-8641-5670cf4614a4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_be28e56d-5640-4bc1-8641-5670cf4614a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_bdb825cb-a6d2-4aca-b7f5-25af2e82ed4e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_5dbbf1fb-fd90-48f7-8add-bb49b2c3f5bd" xlink:to="loc_us-gaap_StockholdersEquity_bdb825cb-a6d2-4aca-b7f5-25af2e82ed4e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_c98dc45e-01ef-4abc-bb6a-81f584fc2eb4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_2622cbd9-239c-425c-9d88-56e5175619ac" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_c98dc45e-01ef-4abc-bb6a-81f584fc2eb4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="simple" xlink:href="tndm-20210630.xsd#CONDENSEDCONSOLIDATEDBALANCESHEETSParenthetical"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDBALANCESHEETSParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_f43fb1ec-beb7-4b97-bf0e-64c595b4b24e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_a2fdae39-361a-4de0-b568-543ff4c911ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f43fb1ec-beb7-4b97-bf0e-64c595b4b24e" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_a2fdae39-361a-4de0-b568-543ff4c911ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_15cc543d-f07f-4359-babd-167e8db5f63e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f43fb1ec-beb7-4b97-bf0e-64c595b4b24e" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_15cc543d-f07f-4359-babd-167e8db5f63e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_483a824b-9d89-47cd-b749-0609506895af" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f43fb1ec-beb7-4b97-bf0e-64c595b4b24e" xlink:to="loc_us-gaap_CommonStockSharesIssued_483a824b-9d89-47cd-b749-0609506895af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_97a9192d-eb9d-4102-a1e4-187271377653" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_f43fb1ec-beb7-4b97-bf0e-64c595b4b24e" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_97a9192d-eb9d-4102-a1e4-187271377653" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVEINCOMELOSS" xlink:type="simple" xlink:href="tndm-20210630.xsd#CONDENSEDCONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVEINCOMELOSS"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFOPERATIONSANDCOMPREHENSIVEINCOMELOSS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_0acfc527-ebd2-4024-bbb7-8421c14cd93a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_0acfc527-ebd2-4024-bbb7-8421c14cd93a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_b08758ae-b6b5-4f86-8164-65af8070c7cf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_b08758ae-b6b5-4f86-8164-65af8070c7cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_f89d2ef5-e625-4adf-8db1-080e19000678" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GrossProfit"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_GrossProfit_f89d2ef5-e625-4adf-8db1-080e19000678" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_880c2d54-69c7-451f-b325-469f240fbc61" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_OperatingExpensesAbstract_880c2d54-69c7-451f-b325-469f240fbc61" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpense_c4128d4d-310c-447f-bcd3-6e25e1c35a5a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_880c2d54-69c7-451f-b325-469f240fbc61" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpense_c4128d4d-310c-447f-bcd3-6e25e1c35a5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_9e38a179-299a-416c-8758-99d4e19afdfb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_880c2d54-69c7-451f-b325-469f240fbc61" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_9e38a179-299a-416c-8758-99d4e19afdfb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_33e168c6-a40d-44b2-865c-084d7cfd5c07" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingExpenses"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_880c2d54-69c7-451f-b325-469f240fbc61" xlink:to="loc_us-gaap_OperatingExpenses_33e168c6-a40d-44b2-865c-084d7cfd5c07" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_0e1415d3-8688-4e4e-aa5c-5fa21fc0b0e4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_OperatingIncomeLoss_0e1415d3-8688-4e4e-aa5c-5fa21fc0b0e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_a4034644-eec2-4c8a-8ec9-36eb0924f5ba" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpenseAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_a4034644-eec2-4c8a-8ec9-36eb0924f5ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestAndOtherIncome_2dccc173-1bf8-4cd3-a02c-64f24f4a3790" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestAndOtherIncome"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_a4034644-eec2-4c8a-8ec9-36eb0924f5ba" xlink:to="loc_us-gaap_InterestAndOtherIncome_2dccc173-1bf8-4cd3-a02c-64f24f4a3790" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseOther_0a50de57-1bfe-4ad5-9359-57547f022373" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseOther"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_a4034644-eec2-4c8a-8ec9-36eb0924f5ba" xlink:to="loc_us-gaap_InterestExpenseOther_0a50de57-1bfe-4ad5-9359-57547f022373" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAdjustmentOfWarrants_cc2b76e9-96e8-4921-99da-0a9647f1a4d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAdjustmentOfWarrants"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_a4034644-eec2-4c8a-8ec9-36eb0924f5ba" xlink:to="loc_us-gaap_FairValueAdjustmentOfWarrants_cc2b76e9-96e8-4921-99da-0a9647f1a4d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_cc6bb2ce-6a12-4b1b-a70c-73dbe3c93d40" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherNonoperatingIncomeExpenseAbstract_a4034644-eec2-4c8a-8ec9-36eb0924f5ba" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_cc6bb2ce-6a12-4b1b-a70c-73dbe3c93d40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_bbaa1270-fd68-4aa4-b0cd-219659983dc7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_bbaa1270-fd68-4aa4-b0cd-219659983dc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_3273ac83-8bb5-4f11-8a5f-8ae8ff1240ee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_3273ac83-8bb5-4f11-8a5f-8ae8ff1240ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_b2adb89f-5e29-4131-9fbf-da21e3aa50aa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_NetIncomeLoss_b2adb89f-5e29-4131-9fbf-da21e3aa50aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_f962e14c-3ef6-4e64-8bb2-4a9cf5d56720" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_f962e14c-3ef6-4e64-8bb2-4a9cf5d56720" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_126d9769-c687-4d26-9b68-a4c99c4b719f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_f962e14c-3ef6-4e64-8bb2-4a9cf5d56720" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_126d9769-c687-4d26-9b68-a4c99c4b719f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_3d687da5-574f-4860-9499-6e16dcae9c87" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_f962e14c-3ef6-4e64-8bb2-4a9cf5d56720" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_3d687da5-574f-4860-9499-6e16dcae9c87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_63187b0c-a7b2-4975-bc9f-6a39ecdfb2c4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_f962e14c-3ef6-4e64-8bb2-4a9cf5d56720" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_63187b0c-a7b2-4975-bc9f-6a39ecdfb2c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_7c3d1e25-0a83-40df-adc3-cbf097079f7e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_EarningsPerShareBasic_7c3d1e25-0a83-40df-adc3-cbf097079f7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_62b22ff3-af1c-4443-a27f-d268b094d443" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_EarningsPerShareDiluted_62b22ff3-af1c-4443-a27f-d268b094d443" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0f5a87b3-eb12-4536-8c92-af9ba465f080" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_0f5a87b3-eb12-4536-8c92-af9ba465f080" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5b4f05f6-2da0-4190-867c-518e652b0968" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_a66a0d47-bfd8-4cf2-965d-07582548d901" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5b4f05f6-2da0-4190-867c-518e652b0968" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" xlink:type="simple" xlink:href="tndm-20210630.xsd#CONDENSEDCONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFSTOCKHOLDERSEQUITY" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_0e051c30-24c8-4340-b951-b4cea4a0b2d5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_dc948d54-8b77-4671-8e86-8d6b0e6b109f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_0e051c30-24c8-4340-b951-b4cea4a0b2d5" xlink:to="loc_us-gaap_StatementTable_dc948d54-8b77-4671-8e86-8d6b0e6b109f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_c4dbc2b6-64fb-4622-9896-7777fdeb94b7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_dc948d54-8b77-4671-8e86-8d6b0e6b109f" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_c4dbc2b6-64fb-4622-9896-7777fdeb94b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_5ae98f37-c4eb-4af4-97d1-abf362587466" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_c4dbc2b6-64fb-4622-9896-7777fdeb94b7" xlink:to="loc_us-gaap_EquityComponentDomain_5ae98f37-c4eb-4af4-97d1-abf362587466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_b9268607-97d1-48b2-98bf-652b3f9d6def" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_5ae98f37-c4eb-4af4-97d1-abf362587466" xlink:to="loc_us-gaap_CommonStockMember_b9268607-97d1-48b2-98bf-652b3f9d6def" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_55ace130-5bd5-4c31-b9c1-d5395e60659b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_5ae98f37-c4eb-4af4-97d1-abf362587466" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_55ace130-5bd5-4c31-b9c1-d5395e60659b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_6ad3a10d-7cab-47a4-a2ee-19a578af3d23" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_5ae98f37-c4eb-4af4-97d1-abf362587466" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_6ad3a10d-7cab-47a4-a2ee-19a578af3d23" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_85b63f41-05d5-49ea-b1a1-5c4b9c0ed7a8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_5ae98f37-c4eb-4af4-97d1-abf362587466" xlink:to="loc_us-gaap_RetainedEarningsMember_85b63f41-05d5-49ea-b1a1-5c4b9c0ed7a8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_86f1ddef-6598-4ff0-a5ad-983712707472" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_dc948d54-8b77-4671-8e86-8d6b0e6b109f" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_86f1ddef-6598-4ff0-a5ad-983712707472" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_fd5392d6-e3e1-40bc-be1e-35ab00a796d6" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_86f1ddef-6598-4ff0-a5ad-983712707472" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_fd5392d6-e3e1-40bc-be1e-35ab00a796d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_1376dd63-9922-4090-938b-ce3a3afcd258" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_fd5392d6-e3e1-40bc-be1e-35ab00a796d6" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_1376dd63-9922-4090-938b-ce3a3afcd258" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_18e783bb-40d1-49b7-a907-a5f18174565a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_dc948d54-8b77-4671-8e86-8d6b0e6b109f" xlink:to="loc_us-gaap_StatementLineItems_18e783bb-40d1-49b7-a907-a5f18174565a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_18e783bb-40d1-49b7-a907-a5f18174565a" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_7e9e5ad2-bc0d-471f-b090-263cb176fd3e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_SharesOutstanding_7e9e5ad2-bc0d-471f-b090-263cb176fd3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_491b2970-b8f8-4f93-8590-11e4e22684ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockholdersEquity_491b2970-b8f8-4f93-8590-11e4e22684ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_66f2a65b-0232-4d2b-bd37-289477f92923" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesStockOptionsExercised_66f2a65b-0232-4d2b-bd37-289477f92923" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_2c9ddf0d-86dd-4f04-ba9f-c53397437748" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueStockOptionsExercised_2c9ddf0d-86dd-4f04-ba9f-c53397437748" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_f04b54ab-b369-40e0-8740-ab6277634bd6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures_f04b54ab-b369-40e0-8740-ab6277634bd6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_fa884c66-8e37-4163-a886-f2dfc557b3f6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures_fa884c66-8e37-4163-a886-f2dfc557b3f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_81f06462-de09-47e9-a013-f5bf93340d72" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans_81f06462-de09-47e9-a013-f5bf93340d72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_6be6907b-0975-409f-ac5c-c57a5dba49a6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan_6be6907b-0975-409f-ac5c-c57a5dba49a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_StockIssuedDuringPeriodSharesCommonStockWarrantsExercised_34fc37f3-fe4c-4bc1-9926-e5e641ff7344" xlink:href="tndm-20210630.xsd#tndm_StockIssuedDuringPeriodSharesCommonStockWarrantsExercised"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_tndm_StockIssuedDuringPeriodSharesCommonStockWarrantsExercised_34fc37f3-fe4c-4bc1-9926-e5e641ff7344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_StockIssuedDuringPeriodValueCommonStockWarrantsExercised_32552b35-7abd-4470-bb35-df74e32c0bb0" xlink:href="tndm-20210630.xsd#tndm_StockIssuedDuringPeriodValueCommonStockWarrantsExercised"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_tndm_StockIssuedDuringPeriodValueCommonStockWarrantsExercised_32552b35-7abd-4470-bb35-df74e32c0bb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_FairValueOfCommonStockWarrantsAtTimeOfExercise_58741232-cd41-4531-87f9-80077eea2d5a" xlink:href="tndm-20210630.xsd#tndm_FairValueOfCommonStockWarrantsAtTimeOfExercise"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_tndm_FairValueOfCommonStockWarrantsAtTimeOfExercise_58741232-cd41-4531-87f9-80077eea2d5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebt_9a61ce77-fa4f-4af1-9660-590e25f3519c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebt"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebt_9a61ce77-fa4f-4af1-9660-590e25f3519c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebtSubsequentAdjustments_93ac370f-70f0-4a16-983b-4e77205d8092" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebtSubsequentAdjustments"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebtSubsequentAdjustments_93ac370f-70f0-4a16-983b-4e77205d8092" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_4ec7523f-e703-492c-903f-6b41bc249078" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_4ec7523f-e703-492c-903f-6b41bc249078" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_e283cb73-c219-48e8-aff6-aa095f3eb53c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_e283cb73-c219-48e8-aff6-aa095f3eb53c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_9ed2e1f3-014a-41bb-88c0-c2a3ec537a0d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_9ed2e1f3-014a-41bb-88c0-c2a3ec537a0d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_6bd9a667-2915-4c67-9791-712c2caf0274" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_NetIncomeLoss_6bd9a667-2915-4c67-9791-712c2caf0274" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharesOutstanding_6346e3ff-1e07-4ea5-9572-47c560229a79" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharesOutstanding"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_SharesOutstanding_6346e3ff-1e07-4ea5-9572-47c560229a79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_aea4c10e-9ae4-4667-b440-9d83774f8b16" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_54e9a4b7-5905-4f9c-b7ff-eac5e38432bd" xlink:to="loc_us-gaap_StockholdersEquity_aea4c10e-9ae4-4667-b440-9d83774f8b16" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingStandardsUpdateExtensibleList_3834cdbb-377b-4cf5-ba76-8fc2d6cf1b71" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingStandardsUpdateExtensibleList"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_18e783bb-40d1-49b7-a907-a5f18174565a" xlink:to="loc_us-gaap_AccountingStandardsUpdateExtensibleList_3834cdbb-377b-4cf5-ba76-8fc2d6cf1b71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="simple" xlink:href="tndm-20210630.xsd#CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWS" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_92c6f527-83ef-4897-8697-3619ad6af1a0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_92c6f527-83ef-4897-8697-3619ad6af1a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProfitLoss_a133bc40-9d98-4dd3-971b-03e08a93cf60" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProfitLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_92c6f527-83ef-4897-8697-3619ad6af1a0" xlink:to="loc_us-gaap_ProfitLoss_a133bc40-9d98-4dd3-971b-03e08a93cf60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_92c6f527-83ef-4897-8697-3619ad6af1a0" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_b8216497-2888-4a14-abe9-12e24e9b515f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_b8216497-2888-4a14-abe9-12e24e9b515f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_f5e41e6d-7469-4c85-804f-331b74bb41cb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfFinancingCostsAndDiscounts"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_AmortizationOfFinancingCostsAndDiscounts_f5e41e6d-7469-4c85-804f-331b74bb41cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_21c7af75-d194-44ca-8e88-438d72f9b8de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_21c7af75-d194-44ca-8e88-438d72f9b8de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWriteDown_0e510aba-d30a-4c78-b7dd-c636d7e68fc8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryWriteDown"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_InventoryWriteDown_0e510aba-d30a-4c78-b7dd-c636d7e68fc8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAdjustmentOfWarrants_c8c41471-8a9e-4538-bf3b-0b23d37b8200" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAdjustmentOfWarrants"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_FairValueAdjustmentOfWarrants_c8c41471-8a9e-4538-bf3b-0b23d37b8200" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_a7ae5806-478f-4fcf-b80f-6a47bdd29ad5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_AccretionAmortizationOfDiscountsAndPremiumsInvestments_a7ae5806-478f-4fcf-b80f-6a47bdd29ad5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_54d389a9-2cc6-4efb-8263-15533022fd32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_54d389a9-2cc6-4efb-8263-15533022fd32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_afc31cac-b634-4c84-b679-c2b82cd084c2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_ShareBasedCompensation_afc31cac-b634-4c84-b679-c2b82cd084c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_f45130b0-1b43-46eb-a2e6-64a04f18af84" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OtherOperatingActivitiesCashFlowStatement"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_15d07147-3c5c-4b24-a694-95e0ce6d68c9" xlink:to="loc_us-gaap_OtherOperatingActivitiesCashFlowStatement_f45130b0-1b43-46eb-a2e6-64a04f18af84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_92c6f527-83ef-4897-8697-3619ad6af1a0" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_cb006008-ed6a-4f2f-a15f-c49be3120c17" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_cb006008-ed6a-4f2f-a15f-c49be3120c17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_4401acf8-a2a4-4601-9b4c-5dc6795cf614" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_4401acf8-a2a4-4601-9b4c-5dc6795cf614" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_30126404-aacd-4978-9613-04cc3e9dd7b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_30126404-aacd-4978-9613-04cc3e9dd7b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_ab1657b9-a5e0-4eb4-b12d-7cb1bb992321" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentAssets"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentAssets_ab1657b9-a5e0-4eb4-b12d-7cb1bb992321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_3d098b8b-3933-4b5a-adbc-1507e4655bcb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_3d098b8b-3933-4b5a-adbc-1507e4655bcb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_cf8542b0-0902-487d-94a2-d8eb1761c05a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_cf8542b0-0902-487d-94a2-d8eb1761c05a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_4cc80bc8-82c1-4c66-9e3b-a7efd339cd9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_4cc80bc8-82c1-4c66-9e3b-a7efd339cd9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherCurrentLiabilities_62a1ee34-10bf-4f5e-9cbb-7e28e521d750" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherCurrentLiabilities"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherCurrentLiabilities_62a1ee34-10bf-4f5e-9cbb-7e28e521d750" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_8d280358-269d-45a0-b8a2-656dd05f86d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_82a6eacd-1fe3-4a35-99aa-aed2e8f33559" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_8d280358-269d-45a0-b8a2-656dd05f86d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2409dd3f-f9e4-495c-aa79-3c6901285a53" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesAbstract_92c6f527-83ef-4897-8697-3619ad6af1a0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2409dd3f-f9e4-495c-aa79-3c6901285a53" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireShortTermInvestments_3bde031a-90a1-4285-b088-f18a5523afc2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireShortTermInvestments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:to="loc_us-gaap_PaymentsToAcquireShortTermInvestments_3bde031a-90a1-4285-b088-f18a5523afc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments_9b3fef34-3a39-4873-bfee-ca243f1fd3c8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments_9b3fef34-3a39-4873-bfee-ca243f1fd3c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfShortTermInvestments_056692c6-4263-49bd-8469-8be909969b4b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromSaleOfShortTermInvestments"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:to="loc_us-gaap_ProceedsFromSaleOfShortTermInvestments_056692c6-4263-49bd-8469-8be909969b4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_240fb54b-57c9-4807-b6b9-fb94155ccf55" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_240fb54b-57c9-4807-b6b9-fb94155ccf55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireIntangibleAssets_598a5415-006a-4e17-916b-71aa6d10c216" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PaymentsToAcquireIntangibleAssets"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:to="loc_us-gaap_PaymentsToAcquireIntangibleAssets_598a5415-006a-4e17-916b-71aa6d10c216" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_d7fe09b6-703d-4131-9b97-44e5aae29d3d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesAbstract_bcad852b-ba4a-4a6d-a429-46a516113743" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_d7fe09b6-703d-4131-9b97-44e5aae29d3d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromConvertibleDebt_541a232f-4ac7-4a19-8bad-6f4fc5c7b138" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromConvertibleDebt"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:to="loc_us-gaap_ProceedsFromConvertibleDebt_541a232f-4ac7-4a19-8bad-6f4fc5c7b138" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_PaymentsForCappedCallOptions_fd921262-e715-4ee0-9438-9c999b32c0eb" xlink:href="tndm-20210630.xsd#tndm_PaymentsForCappedCallOptions"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:to="loc_tndm_PaymentsForCappedCallOptions_fd921262-e715-4ee0-9438-9c999b32c0eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_9924b103-4bfa-4e5b-8f4e-ed958922a382" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_9924b103-4bfa-4e5b-8f4e-ed958922a382" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromWarrantExercises_c0b023ff-2986-453b-a7b5-ea1a31d30cd0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromWarrantExercises"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:to="loc_us-gaap_ProceedsFromWarrantExercises_c0b023ff-2986-453b-a7b5-ea1a31d30cd0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_0fae64fd-4739-4677-8a1d-286869b3716d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesAbstract_59c0ff9f-d3a7-4fac-9b3f-ffaddb6a2dc7" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_0fae64fd-4739-4677-8a1d-286869b3716d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_961a12c1-158d-4a21-b16c-1419214b3152" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_961a12c1-158d-4a21-b16c-1419214b3152" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_03d43374-7cb7-47ed-b76b-979a4fb3772c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_03d43374-7cb7-47ed-b76b-979a4fb3772c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_3085bd02-4d02-47fe-9d1c-0b4dccedca88" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_3085bd02-4d02-47fe-9d1c-0b4dccedca88" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_badfc090-7c64-4fdb-ab13-eaad6da79778" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_badfc090-7c64-4fdb-ab13-eaad6da79778" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowInformationAbstract_874d93d4-508b-4c63-8e17-9f34ac65e7d5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SupplementalCashFlowInformationAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_SupplementalCashFlowInformationAbstract_874d93d4-508b-4c63-8e17-9f34ac65e7d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxesPaid_c9c12625-c929-48f7-8fd6-47e8095ab61b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxesPaid"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowInformationAbstract_874d93d4-508b-4c63-8e17-9f34ac65e7d5" xlink:to="loc_us-gaap_IncomeTaxesPaid_c9c12625-c929-48f7-8fd6-47e8095ab61b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_6c475499-e216-474f-8df1-89e9408319dc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NoncashInvestingAndFinancingItemsAbstract"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_f89e619f-6783-422c-9d4c-570b8b0a63a9" xlink:to="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_6c475499-e216-474f-8df1-89e9408319dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_5fd0141c-f417-4543-9b3f-189cddda4871" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_6c475499-e216-474f-8df1-89e9408319dc" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_5fd0141c-f417-4543-9b3f-189cddda4871" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_c44da998-24ba-402b-a842-23ef55bdecab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CapitalExpendituresIncurredButNotYetPaid"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_6c475499-e216-474f-8df1-89e9408319dc" xlink:to="loc_us-gaap_CapitalExpendituresIncurredButNotYetPaid_c44da998-24ba-402b-a842-23ef55bdecab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_IntangibleCostsInOtherCurrentAndOtherLongTermLiabilities_9bf4abc1-8449-4b81-9d9a-b4b055e84eae" xlink:href="tndm-20210630.xsd#tndm_IntangibleCostsInOtherCurrentAndOtherLongTermLiabilities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NoncashInvestingAndFinancingItemsAbstract_6c475499-e216-474f-8df1-89e9408319dc" xlink:to="loc_tndm_IntangibleCostsInOtherCurrentAndOtherLongTermLiabilities_9bf4abc1-8449-4b81-9d9a-b4b055e84eae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical" xlink:type="simple" xlink:href="tndm-20210630.xsd#CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CONDENSEDCONSOLIDATEDSTATEMENTSOFCASHFLOWSParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_ac59e692-c70e-45d2-b4e8-a362d12cec16" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_649b1964-2078-4c00-89b1-f2bad4631a7f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_ac59e692-c70e-45d2-b4e8-a362d12cec16" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_649b1964-2078-4c00-89b1-f2bad4631a7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/OrganizationandBasisofPresentation" xlink:type="simple" xlink:href="tndm-20210630.xsd#OrganizationandBasisofPresentation"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/OrganizationandBasisofPresentation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_ea39636b-bdba-4eef-b56c-b3f8c41ca770" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_5618b76c-788b-42ba-a4b2-22cc62ce641d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_ea39636b-bdba-4eef-b56c-b3f8c41ca770" xlink:to="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsDisclosureTextBlock_5618b76c-788b-42ba-a4b2-22cc62ce641d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/OrganizationandBasisofPresentationPolicies" xlink:type="simple" xlink:href="tndm-20210630.xsd#OrganizationandBasisofPresentationPolicies"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/OrganizationandBasisofPresentationPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_NatureOfOperationPolicyTextBlock_81e71bcb-ac3a-4ad2-8ec9-ee0bcd3fe2c1" xlink:href="tndm-20210630.xsd#tndm_NatureOfOperationPolicyTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_tndm_NatureOfOperationPolicyTextBlock_81e71bcb-ac3a-4ad2-8ec9-ee0bcd3fe2c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_965c0c24-cf47-4b94-b649-f0712f0f58b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_BasisOfAccountingPolicyPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_BasisOfAccountingPolicyPolicyTextBlock_965c0c24-cf47-4b94-b649-f0712f0f58b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PriorPeriodReclassificationAdjustmentDescription_caf0b5bc-edc5-4681-a1ac-38a0f85056f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PriorPeriodReclassificationAdjustmentDescription"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_PriorPeriodReclassificationAdjustmentDescription_caf0b5bc-edc5-4681-a1ac-38a0f85056f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_41ebf12d-dfad-4774-b67f-105d543a3f66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_UseOfEstimates"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_UseOfEstimates_41ebf12d-dfad-4774-b67f-105d543a3f66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesPolicyTextBlock_4155373c-5008-4ef0-a257-7c1b3b60f986" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ReceivablesPolicyTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_ReceivablesPolicyTextBlock_4155373c-5008-4ef0-a257-7c1b3b60f986" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_d919900b-7aac-4198-8495-d688d243c99d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueOfFinancialInstrumentsPolicy"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_FairValueOfFinancialInstrumentsPolicy_d919900b-7aac-4198-8495-d688d243c99d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_b13f67c9-8ff1-437b-9803-05268bf0ba1a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeLeasesPolicyTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_b13f67c9-8ff1-437b-9803-05268bf0ba1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsIntangibleAssetsPolicy_4df312d6-9ffd-4d0e-8be7-adf61a1d2bbc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_GoodwillAndIntangibleAssetsIntangibleAssetsPolicy"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsIntangibleAssetsPolicy_4df312d6-9ffd-4d0e-8be7-adf61a1d2bbc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_902f7b28-19ad-480b-ac81-12c8f198cb3f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_902f7b28-19ad-480b-ac81-12c8f198cb3f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StandardProductWarrantyPolicy_489f7dd0-675d-4f25-ac4a-f119371e9015" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StandardProductWarrantyPolicy"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_StandardProductWarrantyPolicy_489f7dd0-675d-4f25-ac4a-f119371e9015" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CompensationRelatedCostsPolicyTextBlock_f29d6f90-eaf6-4986-91bc-7049a92a8e70" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CompensationRelatedCostsPolicyTextBlock"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_CompensationRelatedCostsPolicyTextBlock_f29d6f90-eaf6-4986-91bc-7049a92a8e70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_9e7b65ce-3bb5-4af7-8068-226994da1442" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_9e7b65ce-3bb5-4af7-8068-226994da1442" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_287aab0c-1bda-4b88-bdf2-0f8447a3dc17" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_287aab0c-1bda-4b88-bdf2-0f8447a3dc17" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_cfb0d5a0-f842-4745-8e3d-ba220f67b60e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_33e3073e-e7ee-4a07-b548-dd00ecf31e93" xlink:to="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_cfb0d5a0-f842-4745-8e3d-ba220f67b60e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/OrganizationandBasisofPresentationAdditionalInformationDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#OrganizationandBasisofPresentationAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/OrganizationandBasisofPresentationAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_d31e23f0-78f7-490e-8b79-3c204695458c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_OrganizationAndBasisOfPresentationTable_5ea5d3de-6318-4c38-804d-fdd231a737a4" xlink:href="tndm-20210630.xsd#tndm_OrganizationAndBasisOfPresentationTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_d31e23f0-78f7-490e-8b79-3c204695458c" xlink:to="loc_tndm_OrganizationAndBasisOfPresentationTable_5ea5d3de-6318-4c38-804d-fdd231a737a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_a1b9bf01-cde6-4394-b991-1fb383747cfe" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_OrganizationAndBasisOfPresentationTable_5ea5d3de-6318-4c38-804d-fdd231a737a4" xlink:to="loc_srt_ProductOrServiceAxis_a1b9bf01-cde6-4394-b991-1fb383747cfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_e0c43dea-c375-4a59-9ff4-c6db9ab4cd7d" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_a1b9bf01-cde6-4394-b991-1fb383747cfe" xlink:to="loc_srt_ProductsAndServicesDomain_e0c43dea-c375-4a59-9ff4-c6db9ab4cd7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_InsulinPumpMember_55b527df-7d0d-4a09-a18c-7e0a4fa968b3" xlink:href="tndm-20210630.xsd#tndm_InsulinPumpMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_e0c43dea-c375-4a59-9ff4-c6db9ab4cd7d" xlink:to="loc_tndm_InsulinPumpMember_55b527df-7d0d-4a09-a18c-7e0a4fa968b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_2887bb39-1d48-4c14-9950-9bd097fbdbca" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_OrganizationAndBasisOfPresentationTable_5ea5d3de-6318-4c38-804d-fdd231a737a4" xlink:to="loc_srt_RangeAxis_2887bb39-1d48-4c14-9950-9bd097fbdbca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_4df5ca57-be00-407a-b879-9983c96ea4a5" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_2887bb39-1d48-4c14-9950-9bd097fbdbca" xlink:to="loc_srt_RangeMember_4df5ca57-be00-407a-b879-9983c96ea4a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_7def8e5a-cccc-466d-878d-4b2c5771e34b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_4df5ca57-be00-407a-b879-9983c96ea4a5" xlink:to="loc_srt_MinimumMember_7def8e5a-cccc-466d-878d-4b2c5771e34b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_OrganizationAndBasisOfPresentationLineItems_1635ee23-3024-4107-a4ff-34e1e705e342" xlink:href="tndm-20210630.xsd#tndm_OrganizationAndBasisOfPresentationLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_OrganizationAndBasisOfPresentationTable_5ea5d3de-6318-4c38-804d-fdd231a737a4" xlink:to="loc_tndm_OrganizationAndBasisOfPresentationLineItems_1635ee23-3024-4107-a4ff-34e1e705e342" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ProductLifeSpanTerm_a06d3f4e-0f6b-4c8f-a13a-19779e5aa33a" xlink:href="tndm-20210630.xsd#tndm_ProductLifeSpanTerm"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_OrganizationAndBasisOfPresentationLineItems_1635ee23-3024-4107-a4ff-34e1e705e342" xlink:to="loc_tndm_ProductLifeSpanTerm_a06d3f4e-0f6b-4c8f-a13a-19779e5aa33a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_0bac05e6-705d-479b-9e5e-8c4be2cf971f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_26780a5f-7069-4851-997d-3a67ad6b9832" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_0bac05e6-705d-479b-9e5e-8c4be2cf971f" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_26780a5f-7069-4851-997d-3a67ad6b9832" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPoliciesTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_9868c472-2dc8-4377-a31e-30c7f1276ff0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_7420fb8f-85da-4c42-8f70-3dadcd1aabf6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9868c472-2dc8-4377-a31e-30c7f1276ff0" xlink:to="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_7420fb8f-85da-4c42-8f70-3dadcd1aabf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfProductWarrantyLiabilityTableTextBlock_b6f646f2-7041-4e6c-8f76-42b3198f5d1f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfProductWarrantyLiabilityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9868c472-2dc8-4377-a31e-30c7f1276ff0" xlink:to="loc_us-gaap_ScheduleOfProductWarrantyLiabilityTableTextBlock_b6f646f2-7041-4e6c-8f76-42b3198f5d1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_603c1d77-2529-465e-beec-3d98282ee692" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9868c472-2dc8-4377-a31e-30c7f1276ff0" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_603c1d77-2529-465e-beec-3d98282ee692" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_689ddadc-ac39-4bf3-9ad0-485aebafb7dc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_9868c472-2dc8-4377-a31e-30c7f1276ff0" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_689ddadc-ac39-4bf3-9ad0-485aebafb7dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesAdditionalInformationDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPoliciesAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_e2f65350-2592-40ab-91e6-a20e9c2d9db8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:href="tndm-20210630.xsd#tndm_SummaryOfSignificantAccountingPoliciesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_e2f65350-2592-40ab-91e6-a20e9c2d9db8" xlink:to="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_50cf74ed-4689-4215-815a-a98ad622c587" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_us-gaap_DebtInstrumentAxis_50cf74ed-4689-4215-815a-a98ad622c587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_9be655b4-997d-4890-a9e7-f06a3eaa1c64" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_50cf74ed-4689-4215-815a-a98ad622c587" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_9be655b4-997d-4890-a9e7-f06a3eaa1c64" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ConvertibleSeniorNotesMember_319b710a-921a-45ed-9cc1-5a811bd03b4a" xlink:href="tndm-20210630.xsd#tndm_ConvertibleSeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_9be655b4-997d-4890-a9e7-f06a3eaa1c64" xlink:to="loc_tndm_ConvertibleSeniorNotesMember_319b710a-921a-45ed-9cc1-5a811bd03b4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95bc0f4f-ebb1-4b1a-bf1a-23bde0097071" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95bc0f4f-ebb1-4b1a-bf1a-23bde0097071" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4af9cc1e-f81a-424e-9dea-ad7096a68ab9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_95bc0f4f-ebb1-4b1a-bf1a-23bde0097071" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4af9cc1e-f81a-424e-9dea-ad7096a68ab9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_3454982a-2cea-4c00-a556-a429dfc8e625" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_4af9cc1e-f81a-424e-9dea-ad7096a68ab9" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_3454982a-2cea-4c00-a556-a429dfc8e625" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_2ccf85fc-c964-4154-97da-22f95c4c4771" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_2ccf85fc-c964-4154-97da-22f95c4c4771" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_8980912c-2f3d-4e51-8645-189a96d16eee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_2ccf85fc-c964-4154-97da-22f95c4c4771" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_8980912c-2f3d-4e51-8645-189a96d16eee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtMember_032bac9c-3570-447b-bf1f-3162c0950a9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_8980912c-2f3d-4e51-8645-189a96d16eee" xlink:to="loc_us-gaap_ConvertibleDebtMember_032bac9c-3570-447b-bf1f-3162c0950a9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_0dece737-fec5-4009-bd15-5b82347c405a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_0dece737-fec5-4009-bd15-5b82347c405a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_7fe42831-4df4-4153-9502-9296b8a2f44d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsByMajorClassAxis_0dece737-fec5-4009-bd15-5b82347c405a" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_7fe42831-4df4-4153-9502-9296b8a2f44d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TechnologyBasedIntangibleAssetsMember_b1a68e9b-fda2-4581-b856-bb0c3ca0425c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TechnologyBasedIntangibleAssetsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsMajorClassNameDomain_7fe42831-4df4-4153-9502-9296b8a2f44d" xlink:to="loc_us-gaap_TechnologyBasedIntangibleAssetsMember_b1a68e9b-fda2-4581-b856-bb0c3ca0425c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_aad299b9-b042-49cf-9886-610b22e3b298" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_srt_ProductOrServiceAxis_aad299b9-b042-49cf-9886-610b22e3b298" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_53afcd58-5e4b-4593-8dbc-0e1c8e17a101" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_aad299b9-b042-49cf-9886-610b22e3b298" xlink:to="loc_srt_ProductsAndServicesDomain_53afcd58-5e4b-4593-8dbc-0e1c8e17a101" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ComplementaryProductsMember_f5b48cb6-cb86-4797-9a37-d806ae4a583b" xlink:href="tndm-20210630.xsd#tndm_ComplementaryProductsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_53afcd58-5e4b-4593-8dbc-0e1c8e17a101" xlink:to="loc_tndm_ComplementaryProductsMember_f5b48cb6-cb86-4797-9a37-d806ae4a583b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_TandemPumpMember_57c756ae-f4d1-4a61-9db2-69f340d79813" xlink:href="tndm-20210630.xsd#tndm_TandemPumpMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_53afcd58-5e4b-4593-8dbc-0e1c8e17a101" xlink:to="loc_tndm_TandemPumpMember_57c756ae-f4d1-4a61-9db2-69f340d79813" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_SlimCartridgesAndInfusionSetsMember_d6bccf04-5d40-4432-a8dc-bffc06b63ac7" xlink:href="tndm-20210630.xsd#tndm_SlimCartridgesAndInfusionSetsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_53afcd58-5e4b-4593-8dbc-0e1c8e17a101" xlink:to="loc_tndm_SlimCartridgesAndInfusionSetsMember_d6bccf04-5d40-4432-a8dc-bffc06b63ac7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_2db31f61-9758-4be9-bbba-a56f70dcde33" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_2db31f61-9758-4be9-bbba-a56f70dcde33" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_5f9b79ae-3b93-40fa-9695-0ea5e2baeef9" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_2db31f61-9758-4be9-bbba-a56f70dcde33" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_5f9b79ae-3b93-40fa-9695-0ea5e2baeef9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_37e31798-9f51-4083-8782-3efc167b39f1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_5f9b79ae-3b93-40fa-9695-0ea5e2baeef9" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_37e31798-9f51-4083-8782-3efc167b39f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_a52d3a99-347d-4eda-b0ea-9a6df9823c3b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_a52d3a99-347d-4eda-b0ea-9a6df9823c3b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfAdoptionMember_407275d6-f31e-4173-8fb9-a4f65a08ef13" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfAdoptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_a52d3a99-347d-4eda-b0ea-9a6df9823c3b" xlink:to="loc_us-gaap_TypeOfAdoptionMember_407275d6-f31e-4173-8fb9-a4f65a08ef13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingStandardsUpdate202006Member_1c294f11-5dc3-4845-8070-c89c10190a7c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingStandardsUpdate202006Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_407275d6-f31e-4173-8fb9-a4f65a08ef13" xlink:to="loc_us-gaap_AccountingStandardsUpdate202006Member_1c294f11-5dc3-4845-8070-c89c10190a7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:href="tndm-20210630.xsd#tndm_SummaryOfSignificantAccountingPoliciesLineItems"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesTable_af075762-a75c-4be3-bb8f-1802c480252f" xlink:to="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtFairValue_f3bfa763-4c5a-4cc0-8fc4-8a5f987abec1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebtFairValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_LongTermDebtFairValue_f3bfa763-4c5a-4cc0-8fc4-8a5f987abec1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentOwnedAtCost_7e717b67-5d75-407b-a849-483a39315a67" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentOwnedAtCost"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_InvestmentOwnedAtCost_7e717b67-5d75-407b-a849-483a39315a67" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_InvestmentOwnedOwnershipInterest_02d29db9-d096-442d-9c8f-ef57ddc4f877" xlink:href="tndm-20210630.xsd#tndm_InvestmentOwnedOwnershipInterest"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_tndm_InvestmentOwnedOwnershipInterest_02d29db9-d096-442d-9c8f-ef57ddc4f877" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_d6b6b860-d2f9-47ff-9a67-4efad2abb3b2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetUsefulLife"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetUsefulLife_d6b6b860-d2f9-47ff-9a67-4efad2abb3b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ProductsWarrantyPeriod_59d3f5d8-31ef-40e0-9d27-495900adc086" xlink:href="tndm-20210630.xsd#tndm_ProductsWarrantyPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_tndm_ProductsWarrantyPeriod_59d3f5d8-31ef-40e0-9d27-495900adc086" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrual_c72ad2df-fce9-4e7f-9ab9-c4ea18cc7462" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrual"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_ProductWarrantyAccrual_c72ad2df-fce9-4e7f-9ab9-c4ea18cc7462" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_6f12753c-46ec-40aa-aa51-597f4e0e03f9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_6f12753c-46ec-40aa-aa51-597f4e0e03f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_060e29cd-eba5-4a59-8723-8ac5c4aa4c25" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_060e29cd-eba5-4a59-8723-8ac5c4aa4c25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_b5d9a732-10cb-4cca-b822-5aa32b9680a9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_AdditionalPaidInCapital_b5d9a732-10cb-4cca-b822-5aa32b9680a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_548b3d67-dc7a-42a1-9e06-d92c16649710" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtNoncurrent"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_SummaryOfSignificantAccountingPoliciesLineItems_f1a4c3d2-41a1-4288-b8b9-09dd6a5857f1" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_548b3d67-dc7a-42a1-9e06-d92c16649710" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesDeferredRevenueRelatedtoPerformanceObligationsDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPoliciesDeferredRevenueRelatedtoPerformanceObligationsDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesDeferredRevenueRelatedtoPerformanceObligationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_7249ab7a-8e19-40c2-b45f-98bcc07ca1b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_fcd6ff43-be94-46e0-8904-4a522478dacc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_7249ab7a-8e19-40c2-b45f-98bcc07ca1b4" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_fcd6ff43-be94-46e0-8904-4a522478dacc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_64b2954e-8beb-40c1-a548-d77b9103f46a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TimingOfTransferOfGoodOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_fcd6ff43-be94-46e0-8904-4a522478dacc" xlink:to="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_64b2954e-8beb-40c1-a548-d77b9103f46a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_423b7a88-d1c3-4798-b7fb-a45dabd86d32" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TimingOfTransferOfGoodOrServiceDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceAxis_64b2954e-8beb-40c1-a548-d77b9103f46a" xlink:to="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_423b7a88-d1c3-4798-b7fb-a45dabd86d32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransferredOverTimeMember_57952010-5a6b-49f9-8bd1-dff17f807e79" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransferredOverTimeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TimingOfTransferOfGoodOrServiceDomain_423b7a88-d1c3-4798-b7fb-a45dabd86d32" xlink:to="loc_us-gaap_TransferredOverTimeMember_57952010-5a6b-49f9-8bd1-dff17f807e79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_55503e27-0736-47b9-b7da-08f6281a8627" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_fcd6ff43-be94-46e0-8904-4a522478dacc" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_55503e27-0736-47b9-b7da-08f6281a8627" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_cf17501d-f33c-4126-9831-61d7fa3ec102" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_55503e27-0736-47b9-b7da-08f6281a8627" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_cf17501d-f33c-4126-9831-61d7fa3ec102" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_23b25664-a234-4b1c-bb50-eaf14d1228c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContractWithCustomerLiabilityNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_55503e27-0736-47b9-b7da-08f6281a8627" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityNoncurrent_23b25664-a234-4b1c-bb50-eaf14d1228c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiability_8888c9ce-1782-4413-b2fe-8928a7f55303" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ContractWithCustomerLiability"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_55503e27-0736-47b9-b7da-08f6281a8627" xlink:to="loc_us-gaap_ContractWithCustomerLiability_8888c9ce-1782-4413-b2fe-8928a7f55303" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesSummaryofReconciliationofChangeinProductWarrantyLiabilitiesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPoliciesSummaryofReconciliationofChangeinProductWarrantyLiabilitiesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesSummaryofReconciliationofChangeinProductWarrantyLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_0a8919c9-7ae2-4801-b572-65238d0983fc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_0a8919c9-7ae2-4801-b572-65238d0983fc" xlink:to="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrual_089c617e-5d3c-4a7e-b58c-c4ecb66c97c9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrual"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:to="loc_us-gaap_ProductWarrantyAccrual_089c617e-5d3c-4a7e-b58c-c4ecb66c97c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrualWarrantiesIssued_863cdc90-6e51-43db-8687-9114819c018d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrualWarrantiesIssued"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:to="loc_us-gaap_ProductWarrantyAccrualWarrantiesIssued_863cdc90-6e51-43db-8687-9114819c018d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrualPayments_7e2d53d8-ab15-43cd-bd84-b82dcc30d48f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrualPayments"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:to="loc_us-gaap_ProductWarrantyAccrualPayments_7e2d53d8-ab15-43cd-bd84-b82dcc30d48f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrualPreexistingIncreaseDecrease_fb4a9c55-8c90-4ebf-aad1-28130f54c85a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrualPreexistingIncreaseDecrease"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:to="loc_us-gaap_ProductWarrantyAccrualPreexistingIncreaseDecrease_fb4a9c55-8c90-4ebf-aad1-28130f54c85a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrual_f56b8ce1-ac06-4098-b515-56574dd1db15" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrual"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MovementInStandardAndExtendedProductWarrantyIncreaseDecreaseRollForward_b8360c92-05e0-4e49-85ce-2cb0299bd19f" xlink:to="loc_us-gaap_ProductWarrantyAccrual_f56b8ce1-ac06-4098-b515-56574dd1db15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrualClassifiedCurrent_11480c92-a003-429b-ab82-07e0e34d6c9a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrualClassifiedCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_0a8919c9-7ae2-4801-b572-65238d0983fc" xlink:to="loc_us-gaap_ProductWarrantyAccrualClassifiedCurrent_11480c92-a003-429b-ab82-07e0e34d6c9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrualNoncurrent_841b4646-6ff8-48c3-8625-c6ded6f105c6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrualNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_0a8919c9-7ae2-4801-b572-65238d0983fc" xlink:to="loc_us-gaap_ProductWarrantyAccrualNoncurrent_841b4646-6ff8-48c3-8625-c6ded6f105c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductWarrantyAccrual_1d0f2851-4c61-49c8-a01b-a7efee034937" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProductWarrantyAccrual"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_0a8919c9-7ae2-4801-b572-65238d0983fc" xlink:to="loc_us-gaap_ProductWarrantyAccrual_1d0f2851-4c61-49c8-a01b-a7efee034937" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesNumeratorandDenominatoroftheBasicandDilutedNetIncomePerShareComputationsDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPoliciesNumeratorandDenominatoroftheBasicandDilutedNetIncomePerShareComputationsDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesNumeratorandDenominatoroftheBasicandDilutedNetIncomePerShareComputationsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_5b7781fd-0d3a-44c1-9804-f49527e60832" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_35bc76f3-8c87-4a7d-a283-fef773b14c8b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_5b7781fd-0d3a-44c1-9804-f49527e60832" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_35bc76f3-8c87-4a7d-a283-fef773b14c8b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_1e1c59f8-ea1f-4b31-b560-23089286668d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_35bc76f3-8c87-4a7d-a283-fef773b14c8b" xlink:to="loc_us-gaap_AwardTypeAxis_1e1c59f8-ea1f-4b31-b560-23089286668d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3e9f7e12-80a7-4108-a810-88b032cc422f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_1e1c59f8-ea1f-4b31-b560-23089286668d" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3e9f7e12-80a7-4108-a810-88b032cc422f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_66fab087-e28e-479d-b68c-69dc4d1419e9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3e9f7e12-80a7-4108-a810-88b032cc422f" xlink:to="loc_us-gaap_EmployeeStockOptionMember_66fab087-e28e-479d-b68c-69dc4d1419e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_d22e471b-0f31-4e57-a567-b28217a43916" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3e9f7e12-80a7-4108-a810-88b032cc422f" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_d22e471b-0f31-4e57-a567-b28217a43916" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_ffac1906-56a2-4fbd-9d76-6826973b3361" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_3e9f7e12-80a7-4108-a810-88b032cc422f" xlink:to="loc_us-gaap_EmployeeStockMember_ffac1906-56a2-4fbd-9d76-6826973b3361" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_35bc76f3-8c87-4a7d-a283-fef773b14c8b" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_2f5eb7c3-dd49-448d-a253-9ee9371fd040" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_2f5eb7c3-dd49-448d-a253-9ee9371fd040" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_6a17bb47-4be0-4cba-beb1-aef59510390b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_6a17bb47-4be0-4cba-beb1-aef59510390b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_60c31008-66ac-4424-a676-9ffc925d80d6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_60c31008-66ac-4424-a676-9ffc925d80d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_fd7eb8c4-85e0-4982-9887-993f9dbc2bdd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_fd7eb8c4-85e0-4982-9887-993f9dbc2bdd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants_e624cf35-e16a-48f6-babc-26a8c510bcd5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToCallOptionsAndWarrants_e624cf35-e16a-48f6-babc-26a8c510bcd5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_17aad9ff-f021-4f60-ab1a-5a572ba0a601" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToConversionOfDebtSecurities_17aad9ff-f021-4f60-ab1a-5a572ba0a601" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_64b23ba0-de5e-411d-aa4d-4a173df6c934" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_5f3f0121-4753-41cc-86ab-47554dd406f4" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_64b23ba0-de5e-411d-aa4d-4a173df6c934" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesScheduleofAntiDilutiveSecuritiesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#SummaryofSignificantAccountingPoliciesScheduleofAntiDilutiveSecuritiesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/SummaryofSignificantAccountingPoliciesScheduleofAntiDilutiveSecuritiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_a0dd078a-187f-498b-9622-e87c741a3d12" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_eefd0615-dae8-4d72-8fd9-7d891087cefc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_a0dd078a-187f-498b-9622-e87c741a3d12" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_eefd0615-dae8-4d72-8fd9-7d891087cefc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_d9e6c6d3-afb2-40c6-bc10-7ddc4db564db" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_eefd0615-dae8-4d72-8fd9-7d891087cefc" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_d9e6c6d3-afb2-40c6-bc10-7ddc4db564db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_d9e6c6d3-afb2-40c6-bc10-7ddc4db564db" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_daaec123-173a-42b4-9a7e-e78bc8d8435d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:to="loc_us-gaap_EmployeeStockOptionMember_daaec123-173a-42b4-9a7e-e78bc8d8435d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_ca89a74e-2331-48bd-88ca-294f7017df22" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_ca89a74e-2331-48bd-88ca-294f7017df22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_c4a4c958-0845-4e67-a2b6-df9f7e04ddb7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:to="loc_us-gaap_WarrantMember_c4a4c958-0845-4e67-a2b6-df9f7e04ddb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_d20eef8a-4a8e-45a4-ad6f-073ec8502cf2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:to="loc_us-gaap_EmployeeStockMember_d20eef8a-4a8e-45a4-ad6f-073ec8502cf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtSecuritiesMember_13033382-cb4e-48ed-a589-35e5028affc5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtSecuritiesMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_e68153d8-a601-446f-8854-87d255a20ed8" xlink:to="loc_us-gaap_ConvertibleDebtSecuritiesMember_13033382-cb4e-48ed-a589-35e5028affc5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_088a6fe2-894f-4bae-879c-4bf78ee936a0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_eefd0615-dae8-4d72-8fd9-7d891087cefc" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_088a6fe2-894f-4bae-879c-4bf78ee936a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_1c9ec8b1-f1fd-4a84-a364-e292ecc67aae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_088a6fe2-894f-4bae-879c-4bf78ee936a0" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_1c9ec8b1-f1fd-4a84-a364-e292ecc67aae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ShortTermInvestments" xlink:type="simple" xlink:href="tndm-20210630.xsd#ShortTermInvestments"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ShortTermInvestments" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_9e63cadc-39c6-4132-8518-2b6fcd3d8ac2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_aec9fbb2-d644-47d7-ba96-7cc0a569d662" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_9e63cadc-39c6-4132-8518-2b6fcd3d8ac2" xlink:to="loc_us-gaap_InvestmentsInDebtAndMarketableEquitySecuritiesAndCertainTradingAssetsDisclosureTextBlock_aec9fbb2-d644-47d7-ba96-7cc0a569d662" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ShortTermInvestmentsTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#ShortTermInvestmentsTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ShortTermInvestmentsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_957cf8e3-3ce4-4f40-9c29-b84f1670400c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock_e902a3f6-66f1-4ffe-ab58-ff6c5d927362" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_957cf8e3-3ce4-4f40-9c29-b84f1670400c" xlink:to="loc_us-gaap_ScheduleOfCashCashEquivalentsAndShortTermInvestmentsTableTextBlock_e902a3f6-66f1-4ffe-ab58-ff6c5d927362" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ShortTermInvestmentsSummaryofEstimatedFairValueofShortTermInvestmentsDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#ShortTermInvestmentsSummaryofEstimatedFairValueofShortTermInvestmentsDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ShortTermInvestmentsSummaryofEstimatedFairValueofShortTermInvestmentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_73fd4d1c-16c2-4a23-a582-20409f4f789d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsTable_c28cd4be-5b87-4780-b451-781ca4b442c2" xlink:href="tndm-20210630.xsd#tndm_CashCashEquivalentsAndShortTermInvestmentsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InvestmentsDebtAndEquitySecuritiesAbstract_73fd4d1c-16c2-4a23-a582-20409f4f789d" xlink:to="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsTable_c28cd4be-5b87-4780-b451-781ca4b442c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_0dd18f9e-4b2a-4a9c-a2d0-fed6cb7833b9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsTable_c28cd4be-5b87-4780-b451-781ca4b442c2" xlink:to="loc_us-gaap_FinancialInstrumentAxis_0dd18f9e-4b2a-4a9c-a2d0-fed6cb7833b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_0dd18f9e-4b2a-4a9c-a2d0-fed6cb7833b9" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPaperMember_35afaecc-7713-4357-aced-597e204e0ca5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommercialPaperMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:to="loc_us-gaap_CommercialPaperMember_35afaecc-7713-4357-aced-597e204e0ca5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember_f1933df1-e365-4988-8d69-50c4950b7242" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:to="loc_us-gaap_USGovernmentSponsoredEnterprisesDebtSecuritiesMember_f1933df1-e365-4988-8d69-50c4950b7242" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_a1b74d46-8aee-4af7-a05e-2033718a0b6d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_a1b74d46-8aee-4af7-a05e-2033718a0b6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_7a2d1c89-7f29-44bc-b58b-39052feba908" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CorporateDebtSecuritiesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_7a2d1c89-7f29-44bc-b58b-39052feba908" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_SupranationalBondsMember_32678e2f-30c9-44ca-aa33-2ae037bca281" xlink:href="tndm-20210630.xsd#tndm_SupranationalBondsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_585acef8-12ed-4550-bf0e-3e259cc6d154" xlink:to="loc_tndm_SupranationalBondsMember_32678e2f-30c9-44ca-aa33-2ae037bca281" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_b0061561-6bea-4197-98c1-03420348be02" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsTable_c28cd4be-5b87-4780-b451-781ca4b442c2" xlink:to="loc_srt_RangeAxis_b0061561-6bea-4197-98c1-03420348be02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_483fc53b-94c9-4e48-8548-78cbb6abb0fa" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_b0061561-6bea-4197-98c1-03420348be02" xlink:to="loc_srt_RangeMember_483fc53b-94c9-4e48-8548-78cbb6abb0fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_04aa8eac-ffc0-4a70-991a-e795be9179e9" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_483fc53b-94c9-4e48-8548-78cbb6abb0fa" xlink:to="loc_srt_MaximumMember_04aa8eac-ffc0-4a70-991a-e795be9179e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:href="tndm-20210630.xsd#tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsTable_c28cd4be-5b87-4780-b451-781ca4b442c2" xlink:to="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ShortTermInvestmentsMaturity_b3ba639f-5124-46d9-ac9a-dda7e84c9ea8" xlink:href="tndm-20210630.xsd#tndm_ShortTermInvestmentsMaturity"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:to="loc_tndm_ShortTermInvestmentsMaturity_b3ba639f-5124-46d9-ac9a-dda7e84c9ea8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_996966e6-eb59-4fec-8b3b-b5382386a649" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_996966e6-eb59-4fec-8b3b-b5382386a649" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_2b3b7576-8475-4af8-a00b-e0466e0c1b06" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_2b3b7576-8475-4af8-a00b-e0466e0c1b06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_e8846074-53ad-42fb-8a5b-2bef723e3365" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_e8846074-53ad-42fb-8a5b-2bef723e3365" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_57ac058b-f27d-49d7-ba65-315c9cc88146" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_CashCashEquivalentsAndShortTermInvestmentsLineItems_2adf5d23-99d2-45dd-8c5a-08d6bedfdf9b" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_57ac058b-f27d-49d7-ba65-315c9cc88146" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/AccountsReceivableandInventories" xlink:type="simple" xlink:href="tndm-20210630.xsd#AccountsReceivableandInventories"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/AccountsReceivableandInventories" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_254a0f3e-4d8f-4d78-b030-ccc60d83bfca" xlink:href="tndm-20210630.xsd#tndm_AccountsReceivableAndInventoriesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AccountsReceivableAndInventoryDisclosureTextBlock_4325cd4b-d5d3-4624-ac4e-785eb00b1155" xlink:href="tndm-20210630.xsd#tndm_AccountsReceivableAndInventoryDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_254a0f3e-4d8f-4d78-b030-ccc60d83bfca" xlink:to="loc_tndm_AccountsReceivableAndInventoryDisclosureTextBlock_4325cd4b-d5d3-4624-ac4e-785eb00b1155" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#AccountsReceivableandInventoriesTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_1453b2e4-6d2a-4022-8726-31175209fe89" xlink:href="tndm-20210630.xsd#tndm_AccountsReceivableAndInventoriesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_103901ff-8a09-438e-a9de-2b9cbb192eff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_1453b2e4-6d2a-4022-8726-31175209fe89" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_103901ff-8a09-438e-a9de-2b9cbb192eff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableAllowanceForCreditLossTableTextBlock_558a0492-1ff9-45d4-b7ee-a2d47ee27c70" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableAllowanceForCreditLossTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_1453b2e4-6d2a-4022-8726-31175209fe89" xlink:to="loc_us-gaap_AccountsReceivableAllowanceForCreditLossTableTextBlock_558a0492-1ff9-45d4-b7ee-a2d47ee27c70" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_d1db3afa-1610-4f17-96b5-b9afe8d1b3f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_1453b2e4-6d2a-4022-8726-31175209fe89" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_d1db3afa-1610-4f17-96b5-b9afe8d1b3f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesSummaryofAccountsReceivableDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#AccountsReceivableandInventoriesSummaryofAccountsReceivableDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesSummaryofAccountsReceivableDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_aa3ef2a0-2409-4061-9a8b-9ba4f54a02c3" xlink:href="tndm-20210630.xsd#tndm_AccountsReceivableAndInventoriesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableGross_15d9b22f-703a-4413-a805-2344899a23b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_aa3ef2a0-2409-4061-9a8b-9ba4f54a02c3" xlink:to="loc_us-gaap_AccountsReceivableGross_15d9b22f-703a-4413-a805-2344899a23b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_17993aa8-52ee-43df-b963-0268094df71c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_aa3ef2a0-2409-4061-9a8b-9ba4f54a02c3" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_17993aa8-52ee-43df-b963-0268094df71c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNet_74cdf470-61f8-4f50-8779-b1ebf4987d5d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountsReceivableNet"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_aa3ef2a0-2409-4061-9a8b-9ba4f54a02c3" xlink:to="loc_us-gaap_AccountsReceivableNet_74cdf470-61f8-4f50-8779-b1ebf4987d5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesAllowanceForCreditLossesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#AccountsReceivableandInventoriesAllowanceForCreditLossesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesAllowanceForCreditLossesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_a75f1ac0-6e25-4314-aa68-8d432a9a4bf9" xlink:href="tndm-20210630.xsd#tndm_AccountsReceivableAndInventoriesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_9d6a2702-84ef-474b-84ef-0dafd505f999" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_a75f1ac0-6e25-4314-aa68-8d432a9a4bf9" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_9d6a2702-84ef-474b-84ef-0dafd505f999" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_34300212-6b62-4f6d-bdab-3c19e7bac1fe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_9d6a2702-84ef-474b-84ef-0dafd505f999" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_34300212-6b62-4f6d-bdab-3c19e7bac1fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_e3c89bff-0472-4393-9731-1d055e7ad8cd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_9d6a2702-84ef-474b-84ef-0dafd505f999" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_e3c89bff-0472-4393-9731-1d055e7ad8cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs_3a4909cf-6d9c-4598-ad4a-99a599bacb60" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_9d6a2702-84ef-474b-84ef-0dafd505f999" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs_3a4909cf-6d9c-4598-ad4a-99a599bacb60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_1582ca90-cf56-4f90-9b51-2dfb5a87293f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_9d6a2702-84ef-474b-84ef-0dafd505f999" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_1582ca90-cf56-4f90-9b51-2dfb5a87293f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesSummaryofInventoriesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#AccountsReceivableandInventoriesSummaryofInventoriesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/AccountsReceivableandInventoriesSummaryofInventoriesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_03693f61-9d07-474e-a12f-062fdbe975d9" xlink:href="tndm-20210630.xsd#tndm_AccountsReceivableAndInventoriesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterials_88155540-2099-41de-9034-90b00407fbc0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryRawMaterials"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_03693f61-9d07-474e-a12f-062fdbe975d9" xlink:to="loc_us-gaap_InventoryRawMaterials_88155540-2099-41de-9034-90b00407fbc0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcess_f456ae9d-6570-4147-94c8-bf74ca929fce" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryWorkInProcess"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_03693f61-9d07-474e-a12f-062fdbe975d9" xlink:to="loc_us-gaap_InventoryWorkInProcess_f456ae9d-6570-4147-94c8-bf74ca929fce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoods_1e1a6b8b-ef7b-43e9-8625-3fc771115a28" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryFinishedGoods"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_03693f61-9d07-474e-a12f-062fdbe975d9" xlink:to="loc_us-gaap_InventoryFinishedGoods_1e1a6b8b-ef7b-43e9-8625-3fc771115a28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_7a63a0ce-58ba-46ca-8788-dccfb20dae4a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_tndm_AccountsReceivableAndInventoriesDisclosureAbstract_03693f61-9d07-474e-a12f-062fdbe975d9" xlink:to="loc_us-gaap_InventoryNet_7a63a0ce-58ba-46ca-8788-dccfb20dae4a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/FairValueMeasurements" xlink:type="simple" xlink:href="tndm-20210630.xsd#FairValueMeasurements"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/FairValueMeasurements" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_62874653-fd66-452c-be61-e229634d5816" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresTextBlock_4849b1fd-0e20-46ad-9ea5-866cd74d6384" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_62874653-fd66-452c-be61-e229634d5816" xlink:to="loc_us-gaap_FairValueDisclosuresTextBlock_4849b1fd-0e20-46ad-9ea5-866cd74d6384" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/FairValueMeasurementsTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#FairValueMeasurementsTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/FairValueMeasurementsTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_ccc4cae8-3d2c-48af-b347-d5e2b8539d58" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_80628ca7-0ef8-4cdb-a788-9d60c70fc8e0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_ccc4cae8-3d2c-48af-b347-d5e2b8539d58" xlink:to="loc_us-gaap_ScheduleOfFairValueAssetsAndLiabilitiesMeasuredOnRecurringBasisTableTextBlock_80628ca7-0ef8-4cdb-a788-9d60c70fc8e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTableTextBlock_b085fa8f-6ebc-446d-a32b-1b9e6f9a570a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_ccc4cae8-3d2c-48af-b347-d5e2b8539d58" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTableTextBlock_b085fa8f-6ebc-446d-a32b-1b9e6f9a570a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_494a14c6-be6b-457e-9598-5f89518b8760" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_ccc4cae8-3d2c-48af-b347-d5e2b8539d58" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationTextBlock_494a14c6-be6b-457e-9598-5f89518b8760" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/FairValueMeasurementsScheduleofFinancialAssetsandLiabilitiesMeasuredatFairValueonRecurringBasisDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#FairValueMeasurementsScheduleofFinancialAssetsandLiabilitiesMeasuredatFairValueonRecurringBasisDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/FairValueMeasurementsScheduleofFinancialAssetsandLiabilitiesMeasuredatFairValueonRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_c5b11138-25eb-43d6-99f1-36155b06fa2b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_c5b11138-25eb-43d6-99f1-36155b06fa2b" xlink:to="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByMeasurementFrequencyAxis_4ca81163-0ce2-44f5-a579-a65acc703549" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByMeasurementFrequencyAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:to="loc_us-gaap_FairValueByMeasurementFrequencyAxis_4ca81163-0ce2-44f5-a579-a65acc703549" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementFrequencyDomain_a3b6d409-7bd9-4443-badf-b87c94a54f98" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementFrequencyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByMeasurementFrequencyAxis_4ca81163-0ce2-44f5-a579-a65acc703549" xlink:to="loc_us-gaap_FairValueMeasurementFrequencyDomain_a3b6d409-7bd9-4443-badf-b87c94a54f98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsRecurringMember_fdea66db-c870-4928-8e54-6009a389a710" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsRecurringMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementFrequencyDomain_a3b6d409-7bd9-4443-badf-b87c94a54f98" xlink:to="loc_us-gaap_FairValueMeasurementsRecurringMember_fdea66db-c870-4928-8e54-6009a389a710" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinancialInstrumentAxis_fab5f4f1-974f-4c38-8471-f56b7e0537b6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FinancialInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:to="loc_us-gaap_FinancialInstrumentAxis_fab5f4f1-974f-4c38-8471-f56b7e0537b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FinancialInstrumentAxis_fab5f4f1-974f-4c38-8471-f56b7e0537b6" xlink:to="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashEquivalentsMember_82908ae9-9df3-4df9-a47e-8f347cc06723" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashEquivalentsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_us-gaap_CashEquivalentsMember_82908ae9-9df3-4df9-a47e-8f347cc06723" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommercialPaperMember_3631347d-e749-4f7c-b76d-87bb37c1bc6a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommercialPaperMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_us-gaap_CommercialPaperMember_3631347d-e749-4f7c-b76d-87bb37c1bc6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_3dd2b3cd-d1e9-4710-addf-863997e37085" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USGovernmentAgenciesDebtSecuritiesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_us-gaap_USGovernmentAgenciesDebtSecuritiesMember_3dd2b3cd-d1e9-4710-addf-863997e37085" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_USTreasurySecuritiesMember_55e76238-9c55-4afc-a899-61f4990ef161" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_USTreasurySecuritiesMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_us-gaap_USTreasurySecuritiesMember_55e76238-9c55-4afc-a899-61f4990ef161" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CorporateDebtSecuritiesMember_c30f8d60-6607-440e-8296-94b4f809a646" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CorporateDebtSecuritiesMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_us-gaap_CorporateDebtSecuritiesMember_c30f8d60-6607-440e-8296-94b4f809a646" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_SupranationalBondsMember_f5014036-5b2d-4d81-b007-9de2bafc7d00" xlink:href="tndm-20210630.xsd#tndm_SupranationalBondsMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_tndm_SupranationalBondsMember_f5014036-5b2d-4d81-b007-9de2bafc7d00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_62f004a1-f973-4d95-97de-89629e9ad13d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TransfersAndServicingOfFinancialInstrumentsTypesOfFinancialInstrumentsDomain_6a681193-3110-4aef-8981-6656ff9301f4" xlink:to="loc_us-gaap_WarrantMember_62f004a1-f973-4d95-97de-89629e9ad13d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_356ade95-a8fa-409b-b7d7-cd6ae572540e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByFairValueHierarchyLevelAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:to="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_356ade95-a8fa-409b-b7d7-cd6ae572540e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ba42c524-d16f-40ef-98e5-85180f4a1b4c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementsFairValueHierarchyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByFairValueHierarchyLevelAxis_356ade95-a8fa-409b-b7d7-cd6ae572540e" xlink:to="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ba42c524-d16f-40ef-98e5-85180f4a1b4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel1Member_87122377-124b-408f-a113-478ef04592fd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel1Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ba42c524-d16f-40ef-98e5-85180f4a1b4c" xlink:to="loc_us-gaap_FairValueInputsLevel1Member_87122377-124b-408f-a113-478ef04592fd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel2Member_db3eff1b-22f5-4eed-9538-188fecda17df" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel2Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ba42c524-d16f-40ef-98e5-85180f4a1b4c" xlink:to="loc_us-gaap_FairValueInputsLevel2Member_db3eff1b-22f5-4eed-9538-188fecda17df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueInputsLevel3Member_704f9fc6-2758-4362-a658-29e4ab6f9a6d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueInputsLevel3Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueMeasurementsFairValueHierarchyDomain_ba42c524-d16f-40ef-98e5-85180f4a1b4c" xlink:to="loc_us-gaap_FairValueInputsLevel3Member_704f9fc6-2758-4362-a658-29e4ab6f9a6d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_00473266-32d7-4194-8451-07b9ac6afe02" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:to="loc_srt_RangeAxis_00473266-32d7-4194-8451-07b9ac6afe02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_058c96ac-25a8-494b-b9ea-cfc435348db1" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_00473266-32d7-4194-8451-07b9ac6afe02" xlink:to="loc_srt_RangeMember_058c96ac-25a8-494b-b9ea-cfc435348db1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_bce20243-a74f-4072-a6c7-8ce57e124483" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_058c96ac-25a8-494b-b9ea-cfc435348db1" xlink:to="loc_srt_MaximumMember_bce20243-a74f-4072-a6c7-8ce57e124483" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_7c0c49fd-5b84-4293-8676-9744a4f2eb31" xlink:to="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_63a72c8b-a841-4e33-97f9-3eef125639d7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_63a72c8b-a841-4e33-97f9-3eef125639d7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d0929a9b-0d4d-4ff8-84db-a217612c2433" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_d0929a9b-0d4d-4ff8-84db-a217612c2433" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_de760857-dac1-4ce2-a87d-4ce49a0e5bdd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:to="loc_us-gaap_AssetsFairValueDisclosure_de760857-dac1-4ce2-a87d-4ce49a0e5bdd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_4291b661-3046-4c6a-9631-8cfa6ad48f15" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_4291b661-3046-4c6a-9631-8cfa6ad48f15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_c55e09a7-0f4e-4b8f-bc5d-9c08ee702b85" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:to="loc_us-gaap_LiabilitiesFairValueDisclosure_c55e09a7-0f4e-4b8f-bc5d-9c08ee702b85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CashEquivalentsMaturityTerm_5f1fa815-a985-4859-9e8d-90f2ecdc4347" xlink:href="tndm-20210630.xsd#tndm_CashEquivalentsMaturityTerm"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_0872907c-acab-47f6-90aa-b6eebcd7becf" xlink:to="loc_tndm_CashEquivalentsMaturityTerm_5f1fa815-a985-4859-9e8d-90f2ecdc4347" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/FairValueMeasurementsAdditionalInformationDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#FairValueMeasurementsAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/FairValueMeasurementsAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_28efa3a6-1da8-4c3f-a474-9a8f18dc20f3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueByBalanceSheetGroupingTable_0bf1a9d3-1f31-45c2-b155-a962eb20fcd7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueByBalanceSheetGroupingTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_28efa3a6-1da8-4c3f-a474-9a8f18dc20f3" xlink:to="loc_us-gaap_FairValueByBalanceSheetGroupingTable_0bf1a9d3-1f31-45c2-b155-a962eb20fcd7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_ad3623d9-7868-4f67-baa6-7c62a38f3a62" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_0bf1a9d3-1f31-45c2-b155-a962eb20fcd7" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_ad3623d9-7868-4f67-baa6-7c62a38f3a62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_c2ff1892-ef0c-41ab-8da6-70778efa3148" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_ad3623d9-7868-4f67-baa6-7c62a38f3a62" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_c2ff1892-ef0c-41ab-8da6-70778efa3148" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CommonStockWarrantExpiringOctober2022Member_4a6497ee-9090-4347-983b-eb7e343bf775" xlink:href="tndm-20210630.xsd#tndm_CommonStockWarrantExpiringOctober2022Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_c2ff1892-ef0c-41ab-8da6-70778efa3148" xlink:to="loc_tndm_CommonStockWarrantExpiringOctober2022Member_4a6497ee-9090-4347-983b-eb7e343bf775" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_571880ac-baff-404d-accb-33368e683e6c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueByBalanceSheetGroupingTable_0bf1a9d3-1f31-45c2-b155-a962eb20fcd7" xlink:to="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_571880ac-baff-404d-accb-33368e683e6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_650f5510-e525-46d3-9a92-23b15d9af480" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_571880ac-baff-404d-accb-33368e683e6c" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_650f5510-e525-46d3-9a92-23b15d9af480" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodIncreaseDecrease_2c443b62-e65d-4e4d-96f9-d65c387a16b8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodIncreaseDecrease"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueBalanceSheetGroupingFinancialStatementCaptionsLineItems_571880ac-baff-404d-accb-33368e683e6c" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityPeriodIncreaseDecrease_2c443b62-e65d-4e4d-96f9-d65c387a16b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/FairValueMeasurementsScheduleofAssumptionsUsedtoEstimateFairValuesofCommonStockWarrantsDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#FairValueMeasurementsScheduleofAssumptionsUsedtoEstimateFairValuesofCommonStockWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/FairValueMeasurementsScheduleofAssumptionsUsedtoEstimateFairValuesofCommonStockWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_4d24c865-5379-45bc-b167-2e24285703e0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_9fc930d7-4941-48f7-ac0a-7ce60992ff7e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_4d24c865-5379-45bc-b167-2e24285703e0" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_9fc930d7-4941-48f7-ac0a-7ce60992ff7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_9d063b08-d94b-4bfb-a252-1253a1406f2a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_9fc930d7-4941-48f7-ac0a-7ce60992ff7e" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_9d063b08-d94b-4bfb-a252-1253a1406f2a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_d5020a47-3766-4a13-8972-af3dcf035659" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_9d063b08-d94b-4bfb-a252-1253a1406f2a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_d5020a47-3766-4a13-8972-af3dcf035659" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CommonStockWarrantExpiringOctober2022Member_6a76901a-15c5-4051-8a48-de4e40156052" xlink:href="tndm-20210630.xsd#tndm_CommonStockWarrantExpiringOctober2022Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_d5020a47-3766-4a13-8972-af3dcf035659" xlink:to="loc_tndm_CommonStockWarrantExpiringOctober2022Member_6a76901a-15c5-4051-8a48-de4e40156052" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_6e621938-85be-43ac-b70d-40339ae74d11" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_9fc930d7-4941-48f7-ac0a-7ce60992ff7e" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_6e621938-85be-43ac-b70d-40339ae74d11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_4516eba7-44ce-497e-a042-df4fd0fd733d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_6e621938-85be-43ac-b70d-40339ae74d11" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_4516eba7-44ce-497e-a042-df4fd0fd733d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_0ab2ac81-7a92-429b-a7b5-226f7577f1f4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_4516eba7-44ce-497e-a042-df4fd0fd733d" xlink:to="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_0ab2ac81-7a92-429b-a7b5-226f7577f1f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedDividendRateMember_4c7a0484-597a-4b6c-8e8d-da855ec3f592" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MeasurementInputExpectedDividendRateMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_4516eba7-44ce-497e-a042-df4fd0fd733d" xlink:to="loc_us-gaap_MeasurementInputExpectedDividendRateMember_4c7a0484-597a-4b6c-8e8d-da855ec3f592" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputPriceVolatilityMember_4de2817d-1df8-4730-9f3f-ffaef9c82079" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MeasurementInputPriceVolatilityMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_4516eba7-44ce-497e-a042-df4fd0fd733d" xlink:to="loc_us-gaap_MeasurementInputPriceVolatilityMember_4de2817d-1df8-4730-9f3f-ffaef9c82079" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_6f31a981-6231-4a92-b7fa-6cbe55c6ed2c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_4516eba7-44ce-497e-a042-df4fd0fd733d" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_6f31a981-6231-4a92-b7fa-6cbe55c6ed2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_e237d082-2325-4d52-9e86-bbaecc2c4089" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesTable_9fc930d7-4941-48f7-ac0a-7ce60992ff7e" xlink:to="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_e237d082-2325-4d52-9e86-bbaecc2c4089" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_04a61af4-1d06-4433-a687-f97965b86a84" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantsAndRightsOutstandingMeasurementInput"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_e237d082-2325-4d52-9e86-bbaecc2c4089" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_04a61af4-1d06-4433-a687-f97965b86a84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingTerm_bfde930a-7f14-459b-a885-af59f458aed9" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantsAndRightsOutstandingTerm"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueAssetsAndLiabilitiesMeasuredOnRecurringAndNonrecurringBasisValuationTechniquesLineItems_e237d082-2325-4d52-9e86-bbaecc2c4089" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingTerm_bfde930a-7f14-459b-a885-af59f458aed9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/FairValueMeasurementsSummaryofChangesinFairValueofTotalLevel3FinancialAssetsDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#FairValueMeasurementsSummaryofChangesinFairValueofTotalLevel3FinancialAssetsDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/FairValueMeasurementsSummaryofChangesinFairValueofTotalLevel3FinancialAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueDisclosuresAbstract_e3283ac6-7cc5-4b9b-a86f-7148fba62e12" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueDisclosuresAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_52366c16-5aa4-49fd-85d7-3ce97499d68a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueDisclosuresAbstract_e3283ac6-7cc5-4b9b-a86f-7148fba62e12" xlink:to="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_52366c16-5aa4-49fd-85d7-3ce97499d68a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_c9d09de1-82ad-4ebf-bd86-50c7c4942452" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_52366c16-5aa4-49fd-85d7-3ce97499d68a" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_c9d09de1-82ad-4ebf-bd86-50c7c4942452" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_64f5a480-3d43-4c2b-a62f-906c957b1723" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_52366c16-5aa4-49fd-85d7-3ce97499d68a" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilityGainLossIncludedInEarnings_64f5a480-3d43-4c2b-a62f-906c957b1723" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_a07d7aba-0cf0-43d9-91f3-3c8b60a12984" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_52366c16-5aa4-49fd-85d7-3ce97499d68a" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationRecurringBasisLiabilitySettlements_a07d7aba-0cf0-43d9-91f3-3c8b60a12984" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_a11abb73-92cd-4e15-93af-0e373017b521" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_FairValueLiabilitiesMeasuredOnRecurringBasisUnobservableInputReconciliationCalculationRollForward_52366c16-5aa4-49fd-85d7-3ce97499d68a" xlink:to="loc_us-gaap_FairValueMeasurementWithUnobservableInputsReconciliationsRecurringBasisLiabilityValue_a11abb73-92cd-4e15-93af-0e373017b521" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/Leases" xlink:type="simple" xlink:href="tndm-20210630.xsd#Leases"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/Leases" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_1dd5fb12-f1df-4600-ac6a-b75fabe6f473" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_82eded3d-6ed3-4bfa-8e01-2b3b512725b5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_1dd5fb12-f1df-4600-ac6a-b75fabe6f473" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_82eded3d-6ed3-4bfa-8e01-2b3b512725b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/LeasesTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#LeasesTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/LeasesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_2f57bdb1-f646-4194-a8ca-6e46e6c4a2ba" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostTableTextBlock_dd6adc07-c134-445b-b1fc-c33b6ccf4a54" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeaseCostTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_2f57bdb1-f646-4194-a8ca-6e46e6c4a2ba" xlink:to="loc_us-gaap_LeaseCostTableTextBlock_dd6adc07-c134-445b-b1fc-c33b6ccf4a54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_bedd38d5-958f-462d-b2eb-552b95741a9f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_2f57bdb1-f646-4194-a8ca-6e46e6c4a2ba" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_bedd38d5-958f-462d-b2eb-552b95741a9f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/LeasesAdditionalInformationDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#LeasesAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/LeasesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_3bfd662e-4ce5-4aa5-9bae-083602a7d6d0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_264ee972-eb8c-4309-b2c2-9fe61f577e09" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_3bfd662e-4ce5-4aa5-9bae-083602a7d6d0" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_264ee972-eb8c-4309-b2c2-9fe61f577e09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_54b7cc2b-e74d-4c1c-afda-012d2585e0dd" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_264ee972-eb8c-4309-b2c2-9fe61f577e09" xlink:to="loc_srt_RangeAxis_54b7cc2b-e74d-4c1c-afda-012d2585e0dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_7e5b028a-eab4-45ad-8582-2ce39469ea43" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_54b7cc2b-e74d-4c1c-afda-012d2585e0dd" xlink:to="loc_srt_RangeMember_7e5b028a-eab4-45ad-8582-2ce39469ea43" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_cc9f2e62-342e-4739-a1b2-2d084d3509a4" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_7e5b028a-eab4-45ad-8582-2ce39469ea43" xlink:to="loc_srt_MinimumMember_cc9f2e62-342e-4739-a1b2-2d084d3509a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_f2d3a170-aeff-400a-969b-274c10838264" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_7e5b028a-eab4-45ad-8582-2ce39469ea43" xlink:to="loc_srt_MaximumMember_f2d3a170-aeff-400a-969b-274c10838264" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseContractualTermAxis_729acf7b-56b3-42e8-ba6a-cdb6fa1d311e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeaseContractualTermAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_264ee972-eb8c-4309-b2c2-9fe61f577e09" xlink:to="loc_us-gaap_LeaseContractualTermAxis_729acf7b-56b3-42e8-ba6a-cdb6fa1d311e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseContractualTermDomain_e975d398-2af0-4f9a-887c-cff6851ec6fa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeaseContractualTermDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseContractualTermAxis_729acf7b-56b3-42e8-ba6a-cdb6fa1d311e" xlink:to="loc_us-gaap_LeaseContractualTermDomain_e975d398-2af0-4f9a-887c-cff6851ec6fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_VistaSorrentoParkwayLeaseMember_35933ddf-7c20-4479-940d-4ace123e2f2f" xlink:href="tndm-20210630.xsd#tndm_VistaSorrentoParkwayLeaseMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeaseContractualTermDomain_e975d398-2af0-4f9a-887c-cff6851ec6fa" xlink:to="loc_tndm_VistaSorrentoParkwayLeaseMember_35933ddf-7c20-4479-940d-4ace123e2f2f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_264ee972-eb8c-4309-b2c2-9fe61f577e09" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseTermOfContract_ea867d50-2f5e-446c-aa43-3690424942ce" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseTermOfContract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_us-gaap_LesseeOperatingLeaseTermOfContract_ea867d50-2f5e-446c-aa43-3690424942ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AreaOfRealEstateProperty_8c029b9d-ba57-4f9d-9097-1b5abc3ca1ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AreaOfRealEstateProperty"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_us-gaap_AreaOfRealEstateProperty_8c029b9d-ba57-4f9d-9097-1b5abc3ca1ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_LesseeOperatingLeaseNumberOfExtensions_b5dc56f6-5b58-4f3b-90c0-8235230378f9" xlink:href="tndm-20210630.xsd#tndm_LesseeOperatingLeaseNumberOfExtensions"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_tndm_LesseeOperatingLeaseNumberOfExtensions_b5dc56f6-5b58-4f3b-90c0-8235230378f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_4c4007c3-cf82-42fb-a8e5-d16098c52640" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_4c4007c3-cf82-42fb-a8e5-d16098c52640" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_8ebb583c-0499-4e3a-b553-d56f1c632fe3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_8ebb583c-0499-4e3a-b553-d56f1c632fe3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_a5d6cebd-db92-4aa0-9ce2-73b269fd0251" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_us-gaap_OperatingLeaseLiability_a5d6cebd-db92-4aa0-9ce2-73b269fd0251" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeasePayments_ee0a94f3-92f7-4471-96bb-de25127f6748" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeasePayments"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a8a9b18a-90a7-4392-97a0-ba67f271c8d5" xlink:to="loc_us-gaap_OperatingLeasePayments_ee0a94f3-92f7-4471-96bb-de25127f6748" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/LeasesScheduleofLeaseCostLeaseTermDiscountRateOperatingLeasesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#LeasesScheduleofLeaseCostLeaseTermDiscountRateOperatingLeasesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/LeasesScheduleofLeaseCostLeaseTermDiscountRateOperatingLeasesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_e642a8a7-e55e-4470-8235-6214dc918dd2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_517470ff-d990-4ee2-9fb2-e09593d46525" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseCost"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e642a8a7-e55e-4470-8235-6214dc918dd2" xlink:to="loc_us-gaap_OperatingLeaseCost_517470ff-d990-4ee2-9fb2-e09593d46525" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShortTermLeaseCost_ac7b38c8-4473-4a41-9467-33393eb25917" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShortTermLeaseCost"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e642a8a7-e55e-4470-8235-6214dc918dd2" xlink:to="loc_us-gaap_ShortTermLeaseCost_ac7b38c8-4473-4a41-9467-33393eb25917" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_39ab473f-b0be-4793-9760-9601177620c0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeaseCost"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e642a8a7-e55e-4470-8235-6214dc918dd2" xlink:to="loc_us-gaap_LeaseCost_39ab473f-b0be-4793-9760-9601177620c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_876b4562-50d1-4773-b26f-cf55632cff28" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e642a8a7-e55e-4470-8235-6214dc918dd2" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_876b4562-50d1-4773-b26f-cf55632cff28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_969b0755-9877-4fd1-a36a-f2d1f14f1503" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_e642a8a7-e55e-4470-8235-6214dc918dd2" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_969b0755-9877-4fd1-a36a-f2d1f14f1503" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/LeasesScheduleofFutureMinimumPaymentsUnderNoncancellableOperatingLeasesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#LeasesScheduleofFutureMinimumPaymentsUnderNoncancellableOperatingLeasesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/LeasesScheduleofFutureMinimumPaymentsUnderNoncancellableOperatingLeasesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_19ed1624-c1df-4808-bacd-190b1d44412e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_19ed1624-c1df-4808-bacd-190b1d44412e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_89c22055-7ad6-4640-90a7-f4b6c088f842" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_89c22055-7ad6-4640-90a7-f4b6c088f842" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_d5fe75db-5253-4a23-abe9-eaa609233363" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_d5fe75db-5253-4a23-abe9-eaa609233363" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_77e95c7c-7d43-4c48-ab63-2b9ce5543c7e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_77e95c7c-7d43-4c48-ab63-2b9ce5543c7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_1b4cac9a-d880-4bad-aa91-aba71e4194e8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_1b4cac9a-d880-4bad-aa91-aba71e4194e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour_d62513df-8f2b-4547-bf16-39147e10dedf" xlink:href="tndm-20210630.xsd#tndm_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_tndm_LesseeOperatingLeaseLiabilityToBePaidAfterYearFour_d62513df-8f2b-4547-bf16-39147e10dedf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_70b45797-89fc-4211-8a12-d907997447c1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_70b45797-89fc-4211-8a12-d907997447c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_bfabf76a-4baf-4916-b01f-11178567a09d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_bfabf76a-4baf-4916-b01f-11178567a09d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_94b24447-c44a-429a-b536-cedcc360fb9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_OperatingLeaseLiability_94b24447-c44a-429a-b536-cedcc360fb9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_b7c26abf-5b35-4580-9293-97e6180f5c84" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_b7c26abf-5b35-4580-9293-97e6180f5c84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_c548f6a5-5988-4388-aeb8-9437155c0abf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_5318da63-39bc-4a8b-b546-76b5e6f31651" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_c548f6a5-5988-4388-aeb8-9437155c0abf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/LeasesScheduleofFutureMinimumPaymentsUnderNoncancellableOperatingLeasesDetails_1" xlink:type="simple" xlink:href="tndm-20210630.xsd#LeasesScheduleofFutureMinimumPaymentsUnderNoncancellableOperatingLeasesDetails_1"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/LeasesScheduleofFutureMinimumPaymentsUnderNoncancellableOperatingLeasesDetails_1" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotes" xlink:type="simple" xlink:href="tndm-20210630.xsd#ConvertibleSeniorNotes"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotes" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_19fbe233-ba88-4484-ae66-167da24dd8c7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureTextBlock_129ed689-fd64-4363-9cfd-941a1a4b8d65" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_19fbe233-ba88-4484-ae66-167da24dd8c7" xlink:to="loc_us-gaap_DebtDisclosureTextBlock_129ed689-fd64-4363-9cfd-941a1a4b8d65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#ConvertibleSeniorNotesTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_988c7101-a577-4553-a1ad-a538b575282d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtTableTextBlock_28a8332e-1777-4e3a-96b0-d21aaa546bf2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_988c7101-a577-4553-a1ad-a538b575282d" xlink:to="loc_us-gaap_ConvertibleDebtTableTextBlock_28a8332e-1777-4e3a-96b0-d21aaa546bf2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock_648255f5-1411-43fd-812c-bb8a1dad8b46" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_988c7101-a577-4553-a1ad-a538b575282d" xlink:to="loc_us-gaap_InterestIncomeAndInterestExpenseDisclosureTableTextBlock_648255f5-1411-43fd-812c-bb8a1dad8b46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesNarrativeDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#ConvertibleSeniorNotesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_065e6486-6241-4190-a2bd-a9dde5d25c42" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_065e6486-6241-4190-a2bd-a9dde5d25c42" xlink:to="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_6ae307dd-484f-499d-9a09-e7cafed4567b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_us-gaap_DebtInstrumentAxis_6ae307dd-484f-499d-9a09-e7cafed4567b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_5ca5be1c-efe8-4c87-99a6-57bd66605953" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_6ae307dd-484f-499d-9a09-e7cafed4567b" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_5ca5be1c-efe8-4c87-99a6-57bd66605953" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ConvertibleSeniorNotesMember_584e7adc-caec-4298-8ae6-e2c434619905" xlink:href="tndm-20210630.xsd#tndm_ConvertibleSeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_5ca5be1c-efe8-4c87-99a6-57bd66605953" xlink:to="loc_tndm_ConvertibleSeniorNotesMember_584e7adc-caec-4298-8ae6-e2c434619905" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_8b128303-b6b6-43ee-9118-0ef16979970b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_8b128303-b6b6-43ee-9118-0ef16979970b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_27e41ac8-da36-4484-8aa0-207ad934a59d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_8b128303-b6b6-43ee-9118-0ef16979970b" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_27e41ac8-da36-4484-8aa0-207ad934a59d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtMember_862bc1b8-ee2b-4a62-bc9b-2099ebd5b33a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_27e41ac8-da36-4484-8aa0-207ad934a59d" xlink:to="loc_us-gaap_ConvertibleDebtMember_862bc1b8-ee2b-4a62-bc9b-2099ebd5b33a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_1f7d7a52-0231-44ff-b7f9-f1bd6ca47933" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_srt_RangeAxis_1f7d7a52-0231-44ff-b7f9-f1bd6ca47933" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_121b4ebd-4c22-4dee-ab75-57472f7bc9c0" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_1f7d7a52-0231-44ff-b7f9-f1bd6ca47933" xlink:to="loc_srt_RangeMember_121b4ebd-4c22-4dee-ab75-57472f7bc9c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_88b8f0ab-7a34-487e-9ea9-4ee7412af20c" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_121b4ebd-4c22-4dee-ab75-57472f7bc9c0" xlink:to="loc_srt_MinimumMember_88b8f0ab-7a34-487e-9ea9-4ee7412af20c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_e2465fc7-3bc7-4951-a1f6-233899bb902d" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_121b4ebd-4c22-4dee-ab75-57472f7bc9c0" xlink:to="loc_srt_MaximumMember_e2465fc7-3bc7-4951-a1f6-233899bb902d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtConversionByUniqueDescriptionAxis_1acf9bed-1d49-402d-ab61-8488d732a862" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtConversionByUniqueDescriptionAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_us-gaap_DebtConversionByUniqueDescriptionAxis_1acf9bed-1d49-402d-ab61-8488d732a862" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtConversionNameDomain_063c3fc9-6515-4490-8f51-b5d5803a021e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtConversionNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtConversionByUniqueDescriptionAxis_1acf9bed-1d49-402d-ab61-8488d732a862" xlink:to="loc_us-gaap_DebtConversionNameDomain_063c3fc9-6515-4490-8f51-b5d5803a021e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ConversionInstance130Member_51986a3d-7142-493e-bd43-6687e50a6716" xlink:href="tndm-20210630.xsd#tndm_ConversionInstance130Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtConversionNameDomain_063c3fc9-6515-4490-8f51-b5d5803a021e" xlink:to="loc_tndm_ConversionInstance130Member_51986a3d-7142-493e-bd43-6687e50a6716" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ConversionInstance98Member_fccc1ec2-6029-4631-8d4c-b4d0c4f58f2d" xlink:href="tndm-20210630.xsd#tndm_ConversionInstance98Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtConversionNameDomain_063c3fc9-6515-4490-8f51-b5d5803a021e" xlink:to="loc_tndm_ConversionInstance98Member_fccc1ec2-6029-4631-8d4c-b4d0c4f58f2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_61e5f890-edf8-43d2-b575-7170c2170b59" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsForNewAccountingPronouncementsAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_61e5f890-edf8-43d2-b575-7170c2170b59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TypeOfAdoptionMember_fa877ae8-caac-42d9-803e-aca1c38433cc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_TypeOfAdoptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsForNewAccountingPronouncementsAxis_61e5f890-edf8-43d2-b575-7170c2170b59" xlink:to="loc_us-gaap_TypeOfAdoptionMember_fa877ae8-caac-42d9-803e-aca1c38433cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingStandardsUpdate202006Member_ad57a9c6-ae41-49fd-bb39-3aabd4e33f26" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AccountingStandardsUpdate202006Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_TypeOfAdoptionMember_fa877ae8-caac-42d9-803e-aca1c38433cc" xlink:to="loc_us-gaap_AccountingStandardsUpdate202006Member_ad57a9c6-ae41-49fd-bb39-3aabd4e33f26" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_6eacff62-57ee-49a8-830e-3353353bd355" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_6eacff62-57ee-49a8-830e-3353353bd355" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_35580957-76e3-4593-a4c3-1e7413ee99ef" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionAxis_6eacff62-57ee-49a8-830e-3353353bd355" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_35580957-76e3-4593-a4c3-1e7413ee99ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_99af7790-c1d9-4bde-9c72-ae79f7cbe24a" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CumulativeEffectPeriodOfAdoptionDomain_35580957-76e3-4593-a4c3-1e7413ee99ef" xlink:to="loc_srt_CumulativeEffectPeriodOfAdoptionAdjustmentMember_99af7790-c1d9-4bde-9c72-ae79f7cbe24a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_b9cbaffc-1ca7-4a22-a8f3-75033ce39539" xlink:to="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_c2053803-7218-43b2-95de-b5dc1e4813f8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_c2053803-7218-43b2-95de-b5dc1e4813f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_775397b3-f7f7-49f0-a29e-a9e389ee3348" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateStatedPercentage"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentInterestRateStatedPercentage_775397b3-f7f7-49f0-a29e-a9e389ee3348" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfDebt_a89af705-963f-40c1-9b98-25f01731f044" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ProceedsFromIssuanceOfDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfDebt_a89af705-963f-40c1-9b98-25f01731f044" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleConversionRatio1_c2f42afd-8c90-440e-a9df-f3fbf554f9ae" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleConversionRatio1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentConvertibleConversionRatio1_c2f42afd-8c90-440e-a9df-f3fbf554f9ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleConversionPrice1_6330acf2-9632-4614-9b36-869ed7e13819" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleConversionPrice1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentConvertibleConversionPrice1_6330acf2-9632-4614-9b36-869ed7e13819" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger_4a49f944-3508-497a-9734-1e3a07f1c837" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentConvertibleThresholdPercentageOfStockPriceTrigger_4a49f944-3508-497a-9734-1e3a07f1c837" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleThresholdTradingDays_b137c497-91ad-461a-99d0-a1a68efc2f73" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleThresholdTradingDays"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentConvertibleThresholdTradingDays_b137c497-91ad-461a-99d0-a1a68efc2f73" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleThresholdConsecutiveTradingDays1_7ae9eccc-e473-42b6-8635-a4a7d4febeb0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleThresholdConsecutiveTradingDays1"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentConvertibleThresholdConsecutiveTradingDays1_7ae9eccc-e473-42b6-8635-a4a7d4febeb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentRedemptionPricePercentage_6755553e-c677-4059-a2fe-fd4ed81ae3dc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentRedemptionPricePercentage"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentRedemptionPricePercentage_6755553e-c677-4059-a2fe-fd4ed81ae3dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent_bbef9124-e879-4e05-aa4d-217927f1d9a1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent_bbef9124-e879-4e05-aa4d-217927f1d9a1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_44cd056c-24db-4d54-9322-5e17599480ea" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentInterestRateEffectivePercentage"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentInterestRateEffectivePercentage_44cd056c-24db-4d54-9322-5e17599480ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_DebtIssuanceCostsNetEquityComponent_d0377d15-be6f-4b38-9e2a-6903ab96a507" xlink:href="tndm-20210630.xsd#tndm_DebtIssuanceCostsNetEquityComponent"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_tndm_DebtIssuanceCostsNetEquityComponent_d0377d15-be6f-4b38-9e2a-6903ab96a507" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_DebtIssuanceCostsNetLiabilityComponent_904f3bd5-670d-4f07-9762-00106dcbd14b" xlink:href="tndm-20210630.xsd#tndm_DebtIssuanceCostsNetLiabilityComponent"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_tndm_DebtIssuanceCostsNetLiabilityComponent_904f3bd5-670d-4f07-9762-00106dcbd14b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_08b41c42-1490-4342-83cd-fe2bd3f8814a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_08b41c42-1490-4342-83cd-fe2bd3f8814a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_6c7e2192-03cf-46a5-a34c-e4f35db882e1" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_AdditionalPaidInCapital_6c7e2192-03cf-46a5-a34c-e4f35db882e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_125fa3c6-f9e4-4469-b128-a87185441dcd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtNoncurrent"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_125fa3c6-f9e4-4469-b128-a87185441dcd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_dea4bb8d-1781-4f70-81ff-e0a88b0377ab" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_dea4bb8d-1781-4f70-81ff-e0a88b0377ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTerm_5f03b17a-e964-4909-86b2-d02b4e93aa96" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTerm"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_DebtInstrumentTerm_5f03b17a-e964-4909-86b2-d02b4e93aa96" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebtSubsequentAdjustments_98b212d8-9124-42ce-93cd-47900003f7e7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebtSubsequentAdjustments"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebtSubsequentAdjustments_98b212d8-9124-42ce-93cd-47900003f7e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_OptionIndexedToIssuersEquityCapPrice_d4518d41-f1c9-40ed-871b-0556cf624eab" xlink:href="tndm-20210630.xsd#tndm_OptionIndexedToIssuersEquityCapPrice"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_tndm_OptionIndexedToIssuersEquityCapPrice_d4518d41-f1c9-40ed-871b-0556cf624eab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_308ee774-5f74-4200-b0e1-7ee9974956fb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_fd85564f-61bc-44e5-84fc-1683b8247e78" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_308ee774-5f74-4200-b0e1-7ee9974956fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesConvertibleNotesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#ConvertibleSeniorNotesConvertibleNotesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesConvertibleNotesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_a890ab92-f7e4-4657-9d47-b41be9ecff06" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_6089f351-e152-43ff-8135-399fd910f532" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_a890ab92-f7e4-4657-9d47-b41be9ecff06" xlink:to="loc_us-gaap_DebtInstrumentTable_6089f351-e152-43ff-8135-399fd910f532" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_379dfa94-b6a3-4e64-a9e0-bbf3cf245fd5" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_6089f351-e152-43ff-8135-399fd910f532" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_379dfa94-b6a3-4e64-a9e0-bbf3cf245fd5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_ebd7dd64-2d64-4431-aa7e-fb2f1293f802" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_379dfa94-b6a3-4e64-a9e0-bbf3cf245fd5" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_ebd7dd64-2d64-4431-aa7e-fb2f1293f802" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtMember_824e851e-dc9e-4aec-8fad-559c0ea41d69" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_ebd7dd64-2d64-4431-aa7e-fb2f1293f802" xlink:to="loc_us-gaap_ConvertibleDebtMember_824e851e-dc9e-4aec-8fad-559c0ea41d69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_cef9ceab-6929-4580-b22a-51fe9f3f44b4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_6089f351-e152-43ff-8135-399fd910f532" xlink:to="loc_us-gaap_DebtInstrumentAxis_cef9ceab-6929-4580-b22a-51fe9f3f44b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_5f3519aa-1e81-492d-b6fa-3ef2ebda910f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_cef9ceab-6929-4580-b22a-51fe9f3f44b4" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_5f3519aa-1e81-492d-b6fa-3ef2ebda910f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ConvertibleSeniorNotesMember_503f7478-c755-41c2-b9b2-8bb766d3fd6e" xlink:href="tndm-20210630.xsd#tndm_ConvertibleSeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_5f3519aa-1e81-492d-b6fa-3ef2ebda910f" xlink:to="loc_tndm_ConvertibleSeniorNotesMember_503f7478-c755-41c2-b9b2-8bb766d3fd6e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_6089f351-e152-43ff-8135-399fd910f532" xlink:to="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_fdf475c8-23c6-4c52-bfd1-120682296be8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_fdf475c8-23c6-4c52-bfd1-120682296be8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_3e3cffa3-48b8-4af8-819a-f73baa17ac7f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_3e3cffa3-48b8-4af8-819a-f73baa17ac7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentUnamortizedDiscount_7965bd21-5e33-422e-a8e5-c337582138b3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentUnamortizedDiscount"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:to="loc_us-gaap_DebtInstrumentUnamortizedDiscount_7965bd21-5e33-422e-a8e5-c337582138b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_b96bf7ce-b3c3-4003-ac99-16105cd658af" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:to="loc_us-gaap_LongTermDebt_b96bf7ce-b3c3-4003-ac99-16105cd658af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent_17a4b5e8-42f3-4c6a-b63f-9ff14e334ecf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_f3d69851-cb10-4793-90fa-26a8b4b29cb7" xlink:to="loc_us-gaap_DebtInstrumentConvertibleCarryingAmountOfTheEquityComponent_17a4b5e8-42f3-4c6a-b63f-9ff14e334ecf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesInterestExpenseRecognizedDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#ConvertibleSeniorNotesInterestExpenseRecognizedDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/ConvertibleSeniorNotesInterestExpenseRecognizedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_bcfd7dba-2468-4506-8d0d-4e103c45ec66" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_caa1062a-ebdc-445a-b4c9-e1bdd9fd103c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_bcfd7dba-2468-4506-8d0d-4e103c45ec66" xlink:to="loc_us-gaap_DebtInstrumentTable_caa1062a-ebdc-445a-b4c9-e1bdd9fd103c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeAxis_483226cc-4c8d-4707-96c4-d517e54aadaa" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_caa1062a-ebdc-445a-b4c9-e1bdd9fd103c" xlink:to="loc_us-gaap_LongtermDebtTypeAxis_483226cc-4c8d-4707-96c4-d517e54aadaa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongtermDebtTypeDomain_c0070ed6-6e89-463f-87da-46357c00a4c3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LongtermDebtTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeAxis_483226cc-4c8d-4707-96c4-d517e54aadaa" xlink:to="loc_us-gaap_LongtermDebtTypeDomain_c0070ed6-6e89-463f-87da-46357c00a4c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtMember_eea0ebf9-25ef-4658-8d6b-e6423170b29c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LongtermDebtTypeDomain_c0070ed6-6e89-463f-87da-46357c00a4c3" xlink:to="loc_us-gaap_ConvertibleDebtMember_eea0ebf9-25ef-4658-8d6b-e6423170b29c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_4c998c03-9bdb-4e64-8d0c-51011c3dc4ff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_caa1062a-ebdc-445a-b4c9-e1bdd9fd103c" xlink:to="loc_us-gaap_DebtInstrumentAxis_4c998c03-9bdb-4e64-8d0c-51011c3dc4ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_28e7ec29-8230-48d0-a63a-091455f4c757" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_4c998c03-9bdb-4e64-8d0c-51011c3dc4ff" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_28e7ec29-8230-48d0-a63a-091455f4c757" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_ConvertibleSeniorNotesMember_5bb5411e-edcc-45dd-a3ca-988e98181662" xlink:href="tndm-20210630.xsd#tndm_ConvertibleSeniorNotesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_28e7ec29-8230-48d0-a63a-091455f4c757" xlink:to="loc_tndm_ConvertibleSeniorNotesMember_5bb5411e-edcc-45dd-a3ca-988e98181662" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_5940797c-7e88-4665-9228-a8f4ed6e8d2b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_caa1062a-ebdc-445a-b4c9-e1bdd9fd103c" xlink:to="loc_us-gaap_DebtInstrumentLineItems_5940797c-7e88-4665-9228-a8f4ed6e8d2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebtExcludingAmortization_cb429b3e-261b-4ff8-9115-87f8b9695f13" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebtExcludingAmortization"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5940797c-7e88-4665-9228-a8f4ed6e8d2b" xlink:to="loc_us-gaap_InterestExpenseDebtExcludingAmortization_cb429b3e-261b-4ff8-9115-87f8b9695f13" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_bda2c091-2d49-4e3f-94a4-507bc686beff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfFinancingCosts"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5940797c-7e88-4665-9228-a8f4ed6e8d2b" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_bda2c091-2d49-4e3f-94a4-507bc686beff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfDebtDiscountPremium_ebe812d0-6f02-4cba-88db-db2ac83e1d0b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AmortizationOfDebtDiscountPremium"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5940797c-7e88-4665-9228-a8f4ed6e8d2b" xlink:to="loc_us-gaap_AmortizationOfDebtDiscountPremium_ebe812d0-6f02-4cba-88db-db2ac83e1d0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpenseDebt_66b30157-6a57-4b02-b12c-04b40dd0b10b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_InterestExpenseDebt"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_5940797c-7e88-4665-9228-a8f4ed6e8d2b" xlink:to="loc_us-gaap_InterestExpenseDebt_66b30157-6a57-4b02-b12c-04b40dd0b10b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquity" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquity"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_064a7e68-0e7f-4bd1-9ad0-b7d80699620d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_20c2d49b-7de9-4ab5-bc81-b29c96be1f4b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockholdersEquityNoteDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_064a7e68-0e7f-4bd1-9ad0-b7d80699620d" xlink:to="loc_us-gaap_StockholdersEquityNoteDisclosureTextBlock_20c2d49b-7de9-4ab5-bc81-b29c96be1f4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquityTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquityTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_f843de2a-836c-44c7-920b-b476760854f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_db632c37-96ff-4ee0-ba80-236f0b9a6254" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f843de2a-836c-44c7-920b-b476760854f7" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_db632c37-96ff-4ee0-ba80-236f0b9a6254" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_a3d3a6c5-6494-443b-9c3f-269f1f03c50e" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f843de2a-836c-44c7-920b-b476760854f7" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_a3d3a6c5-6494-443b-9c3f-269f1f03c50e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardEmployeeStockPurchasePlanValuationAssumptionsTableTextBlock_198b26c8-393b-4783-9574-9f7b9d86541d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardEmployeeStockPurchasePlanValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f843de2a-836c-44c7-920b-b476760854f7" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardEmployeeStockPurchasePlanValuationAssumptionsTableTextBlock_198b26c8-393b-4783-9574-9f7b9d86541d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_c1265958-7904-46ab-ba2a-bf189549718a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f843de2a-836c-44c7-920b-b476760854f7" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_c1265958-7904-46ab-ba2a-bf189549718a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquityScheduleofSharesofCommonStockReservedforFutureIssuanceDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquityScheduleofSharesofCommonStockReservedforFutureIssuanceDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquityScheduleofSharesofCommonStockReservedforFutureIssuanceDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_4db77ef4-1d66-490c-aee0-f4b7bba30394" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_df70519d-41fb-45b2-9808-778c34b9944b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_4db77ef4-1d66-490c-aee0-f4b7bba30394" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_df70519d-41fb-45b2-9808-778c34b9944b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_d61c8f89-6bee-4314-8bd2-bb20ef13bf57" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_df70519d-41fb-45b2-9808-778c34b9944b" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_d61c8f89-6bee-4314-8bd2-bb20ef13bf57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_d61c8f89-6bee-4314-8bd2-bb20ef13bf57" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtSecuritiesMember_4e931851-54b7-4f9e-b88a-ca5334ba27ba" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConvertibleDebtSecuritiesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:to="loc_us-gaap_ConvertibleDebtSecuritiesMember_4e931851-54b7-4f9e-b88a-ca5334ba27ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_996c68e9-dd41-4c0e-a670-05e8594d660d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:to="loc_us-gaap_WarrantMember_996c68e9-dd41-4c0e-a670-05e8594d660d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_StockOptionsIssuedAndOutstandingMember_835a78da-00a8-488b-b328-8d1687fcb133" xlink:href="tndm-20210630.xsd#tndm_StockOptionsIssuedAndOutstandingMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:to="loc_tndm_StockOptionsIssuedAndOutstandingMember_835a78da-00a8-488b-b328-8d1687fcb133" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_fabf8069-1913-4478-a580-741d8c809bfe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_fabf8069-1913-4478-a580-741d8c809bfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockCompensationPlanMember_0248302e-aa33-429d-bc19-2e75e33c5abe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StockCompensationPlanMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:to="loc_us-gaap_StockCompensationPlanMember_0248302e-aa33-429d-bc19-2e75e33c5abe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_AuthorizedForFutureOptionGrantsMember_a2af1117-bef4-427b-bbf6-df8b95b74d82" xlink:href="tndm-20210630.xsd#tndm_AuthorizedForFutureOptionGrantsMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_ce3f9f8a-1ea8-42f2-b869-51773c65d943" xlink:to="loc_tndm_AuthorizedForFutureOptionGrantsMember_a2af1117-bef4-427b-bbf6-df8b95b74d82" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d2fe223e-bc70-4734-a8ce-e2e71e2dff49" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_df70519d-41fb-45b2-9808-778c34b9944b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d2fe223e-bc70-4734-a8ce-e2e71e2dff49" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_57ee5bd7-cce2-4d1d-a5a2-612b36661152" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommonStockCapitalSharesReservedForFutureIssuance"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_d2fe223e-bc70-4734-a8ce-e2e71e2dff49" xlink:to="loc_us-gaap_CommonStockCapitalSharesReservedForFutureIssuance_57ee5bd7-cce2-4d1d-a5a2-612b36661152" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquityScheduleofCommonStockWarrantsDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquityScheduleofCommonStockWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquityScheduleofCommonStockWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_b95cde89-a293-4e3f-8308-0748878002b6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_78298ea3-1404-4563-bafb-6398d526c84d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_b95cde89-a293-4e3f-8308-0748878002b6" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_78298ea3-1404-4563-bafb-6398d526c84d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_ef952eb2-b520-4b48-b81b-71c5dddea900" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_78298ea3-1404-4563-bafb-6398d526c84d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_ef952eb2-b520-4b48-b81b-71c5dddea900" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_5ee3622b-1879-4d1e-ac04-44366eeb7bb3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_ef952eb2-b520-4b48-b81b-71c5dddea900" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_5ee3622b-1879-4d1e-ac04-44366eeb7bb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CommonStockWarrantExpiringOctober2022Member_c669acef-102a-4d7e-9504-550e25ad2dbf" xlink:href="tndm-20210630.xsd#tndm_CommonStockWarrantExpiringOctober2022Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_5ee3622b-1879-4d1e-ac04-44366eeb7bb3" xlink:to="loc_tndm_CommonStockWarrantExpiringOctober2022Member_c669acef-102a-4d7e-9504-550e25ad2dbf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CommonStockWarrantExpiringMarch2027Member_3efe636b-7ae7-435a-9af1-1c8292cd2c6f" xlink:href="tndm-20210630.xsd#tndm_CommonStockWarrantExpiringMarch2027Member"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_5ee3622b-1879-4d1e-ac04-44366eeb7bb3" xlink:to="loc_tndm_CommonStockWarrantExpiringMarch2027Member_3efe636b-7ae7-435a-9af1-1c8292cd2c6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_CommonStockWarrantExpiringBetweenAugust2021andAugust2022Member_50d0c34a-fb40-4b81-ba18-6032c72dd3c6" xlink:href="tndm-20210630.xsd#tndm_CommonStockWarrantExpiringBetweenAugust2021andAugust2022Member"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_5ee3622b-1879-4d1e-ac04-44366eeb7bb3" xlink:to="loc_tndm_CommonStockWarrantExpiringBetweenAugust2021andAugust2022Member_50d0c34a-fb40-4b81-ba18-6032c72dd3c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_c5e7ba07-d4bc-4235-9986-921e410985f2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_78298ea3-1404-4563-bafb-6398d526c84d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_c5e7ba07-d4bc-4235-9986-921e410985f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_c7bd8482-8ac6-48ad-8024-b710ca4c2f71" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_c5e7ba07-d4bc-4235-9986-921e410985f2" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_c7bd8482-8ac6-48ad-8024-b710ca4c2f71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightOutstanding_a0a47ee5-2a28-4a1a-a591-9f54cf35d5e3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_c5e7ba07-d4bc-4235-9986-921e410985f2" xlink:to="loc_us-gaap_ClassOfWarrantOrRightOutstanding_a0a47ee5-2a28-4a1a-a591-9f54cf35d5e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquityAdditionalInformationDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquityAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquityAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_983da8eb-9ff9-4da1-b92c-aa1f19b65cc8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_983da8eb-9ff9-4da1-b92c-aa1f19b65cc8" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_3157f696-5f82-47ef-9dd2-58ddaea38385" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_3157f696-5f82-47ef-9dd2-58ddaea38385" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_effeb130-df63-44ae-aa7e-b16b62067d18" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_3157f696-5f82-47ef-9dd2-58ddaea38385" xlink:to="loc_us-gaap_EquityComponentDomain_effeb130-df63-44ae-aa7e-b16b62067d18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantMember_192592a6-bd2f-42af-8ca5-abec5d8b1714" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_WarrantMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_effeb130-df63-44ae-aa7e-b16b62067d18" xlink:to="loc_us-gaap_WarrantMember_192592a6-bd2f-42af-8ca5-abec5d8b1714" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_e56ae17b-27c3-4d07-8513-f6184dfbc555" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_us-gaap_AwardTypeAxis_e56ae17b-27c3-4d07-8513-f6184dfbc555" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1102dc14-c39d-47a7-be41-5ed601065357" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_e56ae17b-27c3-4d07-8513-f6184dfbc555" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1102dc14-c39d-47a7-be41-5ed601065357" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_699689ac-d307-4ef1-b4f5-8057f6571cc8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1102dc14-c39d-47a7-be41-5ed601065357" xlink:to="loc_us-gaap_EmployeeStockOptionMember_699689ac-d307-4ef1-b4f5-8057f6571cc8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_f1503652-c622-444e-8867-c7bffbab6676" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1102dc14-c39d-47a7-be41-5ed601065357" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_f1503652-c622-444e-8867-c7bffbab6676" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PerformanceSharesMember_b0dd7701-0a20-423c-953f-0c4f1a63cef3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PerformanceSharesMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_1102dc14-c39d-47a7-be41-5ed601065357" xlink:to="loc_us-gaap_PerformanceSharesMember_b0dd7701-0a20-423c-953f-0c4f1a63cef3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_65a469a0-e0a3-4b61-af25-1f86821e9d6a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_65a469a0-e0a3-4b61-af25-1f86821e9d6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_f0a9f3c9-7909-409c-9096-8ddda583275a" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_65a469a0-e0a3-4b61-af25-1f86821e9d6a" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_f0a9f3c9-7909-409c-9096-8ddda583275a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_3919b8df-a94d-4a31-849c-78e948643524" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_f0a9f3c9-7909-409c-9096-8ddda583275a" xlink:to="loc_us-gaap_EmployeeStockMember_3919b8df-a94d-4a31-849c-78e948643524" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_c3929f4d-0d6e-4f4f-8338-5977eb2a80ca" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_us-gaap_PlanNameAxis_c3929f4d-0d6e-4f4f-8338-5977eb2a80ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_d7d77482-08b4-4990-b336-f11856876210" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_c3929f4d-0d6e-4f4f-8338-5977eb2a80ca" xlink:to="loc_us-gaap_PlanNameDomain_d7d77482-08b4-4990-b336-f11856876210" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_TwoThousandThirteenPlanMember_8a951a62-4c7b-4d1f-8932-14e00ca5e663" xlink:href="tndm-20210630.xsd#tndm_TwoThousandThirteenPlanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_d7d77482-08b4-4990-b336-f11856876210" xlink:to="loc_tndm_TwoThousandThirteenPlanMember_8a951a62-4c7b-4d1f-8932-14e00ca5e663" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingAxis_da6ebd04-25a2-474b-814d-ea106523bfdc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VestingAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_us-gaap_VestingAxis_da6ebd04-25a2-474b-814d-ea106523bfdc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VestingDomain_0c42e19f-4a96-4f51-bee3-9a2188eda888" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_VestingDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingAxis_da6ebd04-25a2-474b-814d-ea106523bfdc" xlink:to="loc_us-gaap_VestingDomain_0c42e19f-4a96-4f51-bee3-9a2188eda888" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_f0b07aa6-2ea0-437f-96ab-a7e2eb3760e3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_0c42e19f-4a96-4f51-bee3-9a2188eda888" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheOneMember_f0b07aa6-2ea0-437f-96ab-a7e2eb3760e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationAwardTrancheTwoMember_97a06e8a-b1c7-4e3e-b52d-9b2350ea1a7f" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationAwardTrancheTwoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_0c42e19f-4a96-4f51-bee3-9a2188eda888" xlink:to="loc_us-gaap_ShareBasedCompensationAwardTrancheTwoMember_97a06e8a-b1c7-4e3e-b52d-9b2350ea1a7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_VestAnnuallyOverOneToThreeYearsMember_a030d547-f1d0-42bb-b90c-a525d1ee3dcb" xlink:href="tndm-20210630.xsd#tndm_VestAnnuallyOverOneToThreeYearsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VestingDomain_0c42e19f-4a96-4f51-bee3-9a2188eda888" xlink:to="loc_tndm_VestAnnuallyOverOneToThreeYearsMember_a030d547-f1d0-42bb-b90c-a525d1ee3dcb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_e17b3fed-f684-49fe-b7db-cf03c05bbc48" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeAxis"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_srt_RangeAxis_e17b3fed-f684-49fe-b7db-cf03c05bbc48" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_aa7e7a21-4553-4172-a830-03a2d7f12321" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_e17b3fed-f684-49fe-b7db-cf03c05bbc48" xlink:to="loc_srt_RangeMember_aa7e7a21-4553-4172-a830-03a2d7f12321" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_44ef1c7b-9b4b-41f6-87ff-de9b9e0b3677" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_MaximumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_aa7e7a21-4553-4172-a830-03a2d7f12321" xlink:to="loc_srt_MaximumMember_44ef1c7b-9b4b-41f6-87ff-de9b9e0b3677" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_73619bad-342a-4244-9801-49ea69714eff" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight_a223a5a8-0abe-4b86-bc73-20a5ef54b8ee" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByEachWarrantOrRight_a223a5a8-0abe-4b86-bc73-20a5ef54b8ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod_b820040f-ad71-4bcd-b40b-c4534f02d436" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardSharesIssuedInPeriod_b820040f-ad71-4bcd-b40b-c4534f02d436" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_OfferingPeriod_dcc68d24-3899-4d5d-9b19-78488fc5ddf8" xlink:href="tndm-20210630.xsd#tndm_OfferingPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_tndm_OfferingPeriod_dcc68d24-3899-4d5d-9b19-78488fc5ddf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_NumberOfPurchasePeriods_b0b90ec2-cb53-421d-9092-36de898841c8" xlink:href="tndm-20210630.xsd#tndm_NumberOfPurchasePeriods"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_tndm_NumberOfPurchasePeriods_b0b90ec2-cb53-421d-9092-36de898841c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_PurchasePeriod_465b0c37-05d5-42ed-9867-a1b7d0f14bf9" xlink:href="tndm-20210630.xsd#tndm_PurchasePeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_tndm_PurchasePeriod_465b0c37-05d5-42ed-9867-a1b7d0f14bf9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_1d2fbea2-6a6a-410f-9dd2-1a333f31fdfe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_1d2fbea2-6a6a-410f-9dd2-1a333f31fdfe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_6a1b568e-e2f4-4e20-8254-9909473d07bc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_6a1b568e-e2f4-4e20-8254-9909473d07bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_e162247c-03f9-4490-80bf-d748dea1d169" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardAwardVestingRightsPercentage_e162247c-03f9-4490-80bf-d748dea1d169" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_a97ac648-50b0-4efa-aa26-1b18480346d4" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardAwardVestingPeriod1_a97ac648-50b0-4efa-aa26-1b18480346d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedAmount_5f580fca-3414-4a35-b1c6-481577923e39" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedAmount"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_caa19ea7-7e90-4e6f-b448-62480f0f6916" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsCapitalizedAmount_5f580fca-3414-4a35-b1c6-481577923e39" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquityScheduleofAssumptionsUsedinBlackScholesOptionPricingModelDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquityScheduleofAssumptionsUsedinBlackScholesOptionPricingModelDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquityScheduleofAssumptionsUsedinBlackScholesOptionPricingModelDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_64a0c471-f9ee-4413-ba0b-15a9f4800fdd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ed7f4af3-5c68-475d-bbba-b23dc308dfa6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_64a0c471-f9ee-4413-ba0b-15a9f4800fdd" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ed7f4af3-5c68-475d-bbba-b23dc308dfa6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_07d163ee-1bb7-49ea-bbdb-e31fe6477ccf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ed7f4af3-5c68-475d-bbba-b23dc308dfa6" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_07d163ee-1bb7-49ea-bbdb-e31fe6477ccf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_419ed24c-09c0-4e88-b01c-60750f6be008" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_07d163ee-1bb7-49ea-bbdb-e31fe6477ccf" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_419ed24c-09c0-4e88-b01c-60750f6be008" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockOptionMember_507be085-5180-4f94-864d-361c583da474" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_419ed24c-09c0-4e88-b01c-60750f6be008" xlink:to="loc_us-gaap_EmployeeStockOptionMember_507be085-5180-4f94-864d-361c583da474" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockUnitsRSUMember_946dba71-4638-4529-9026-682093061a92" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RestrictedStockUnitsRSUMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_419ed24c-09c0-4e88-b01c-60750f6be008" xlink:to="loc_us-gaap_RestrictedStockUnitsRSUMember_946dba71-4638-4529-9026-682093061a92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeStockMember_74222b79-e46a-4ccd-bacd-9073dc070df7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EmployeeStockMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_419ed24c-09c0-4e88-b01c-60750f6be008" xlink:to="loc_us-gaap_EmployeeStockMember_74222b79-e46a-4ccd-bacd-9073dc070df7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_ed7f4af3-5c68-475d-bbba-b23dc308dfa6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_1ada5cee-1db8-43de-8243-48ba8437f0b3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_1ada5cee-1db8-43de-8243-48ba8437f0b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_48b2faec-e9f4-4d50-971b-f6b1c29c566c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_48b2faec-e9f4-4d50-971b-f6b1c29c566c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_f90b634b-73ea-4d40-9fde-8b7949f0baa3" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_f90b634b-73ea-4d40-9fde-8b7949f0baa3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_96b61f50-8ac1-44b7-9915-24fe5d5fc2e6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_96b61f50-8ac1-44b7-9915-24fe5d5fc2e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_547e9b59-5627-45f7-b25a-f459a0b0370c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_277548d9-453e-4445-bad0-86cda6a37651" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_547e9b59-5627-45f7-b25a-f459a0b0370c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/StockholdersEquitySummaryforAllocationofStockBasedCompensationExpenseDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#StockholdersEquitySummaryforAllocationofStockBasedCompensationExpenseDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/StockholdersEquitySummaryforAllocationofStockBasedCompensationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_368f1092-05ca-4a3a-a875-dc5501c4d2fb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3badc669-aa91-4be6-9f2f-26fb5cdb6064" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_368f1092-05ca-4a3a-a875-dc5501c4d2fb" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3badc669-aa91-4be6-9f2f-26fb5cdb6064" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_397ca95c-e8e4-4c36-b1b0-59f486fadcb2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3badc669-aa91-4be6-9f2f-26fb5cdb6064" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_397ca95c-e8e4-4c36-b1b0-59f486fadcb2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_0535bd58-d7cd-4820-a70a-37e94d9274eb" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_397ca95c-e8e4-4c36-b1b0-59f486fadcb2" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_0535bd58-d7cd-4820-a70a-37e94d9274eb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfSalesMember_eac40736-ad7f-4bc2-a774-36f1e6319a9c" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CostOfSalesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_0535bd58-d7cd-4820-a70a-37e94d9274eb" xlink:to="loc_us-gaap_CostOfSalesMember_eac40736-ad7f-4bc2-a774-36f1e6319a9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_a761608f-2fb3-4d31-9bc0-c459b6d5f351" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SellingGeneralAndAdministrativeExpensesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_0535bd58-d7cd-4820-a70a-37e94d9274eb" xlink:to="loc_us-gaap_SellingGeneralAndAdministrativeExpensesMember_a761608f-2fb3-4d31-9bc0-c459b6d5f351" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_26ecad5b-1e98-4961-a396-663860c16cc6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_0535bd58-d7cd-4820-a70a-37e94d9274eb" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_26ecad5b-1e98-4961-a396-663860c16cc6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_695921b4-f954-45a5-b452-5dfcbcbb2776" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_3badc669-aa91-4be6-9f2f-26fb5cdb6064" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_695921b4-f954-45a5-b452-5dfcbcbb2776" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_b1a5785d-806f-4b72-8cc0-6950b847b6e0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_695921b4-f954-45a5-b452-5dfcbcbb2776" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_b1a5785d-806f-4b72-8cc0-6950b847b6e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/IncomeTaxes" xlink:type="simple" xlink:href="tndm-20210630.xsd#IncomeTaxes"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/IncomeTaxes" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_97b5047e-905b-49cd-a53a-663856242144" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureTextBlock_de05586b-59f0-4588-90b6-3ab3f064e4f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_97b5047e-905b-49cd-a53a-663856242144" xlink:to="loc_us-gaap_IncomeTaxDisclosureTextBlock_de05586b-59f0-4588-90b6-3ab3f064e4f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/IncomeTaxesDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#IncomeTaxesDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/IncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxDisclosureAbstract_a94cdc79-ce73-4add-a656-dc20a51c314d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_93ba1208-caea-4749-8c62-20c62ffd47de" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_a94cdc79-ce73-4add-a656-dc20a51c314d" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_93ba1208-caea-4749-8c62-20c62ffd47de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_93998745-6cda-4497-9ed9-22681bd5d9f7" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeTaxDisclosureAbstract_a94cdc79-ce73-4add-a656-dc20a51c314d" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_93998745-6cda-4497-9ed9-22681bd5d9f7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformation" xlink:type="simple" xlink:href="tndm-20210630.xsd#BusinessSegmentandGeographicInformation"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_37755299-a4fe-487d-9cb5-de180ee268d6" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_60feb782-f492-49f7-b9d0-24d19aec2e11" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_37755299-a4fe-487d-9cb5-de180ee268d6" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_60feb782-f492-49f7-b9d0-24d19aec2e11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformationTables" xlink:type="simple" xlink:href="tndm-20210630.xsd#BusinessSegmentandGeographicInformationTables"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformationTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_f1364d0e-4209-4931-8380-3e9d3d1cc587" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_2e6e6a5e-4520-4b36-a32f-4254c97f92f0" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_f1364d0e-4209-4931-8380-3e9d3d1cc587" xlink:to="loc_us-gaap_DisaggregationOfRevenueTableTextBlock_2e6e6a5e-4520-4b36-a32f-4254c97f92f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformationAdditionalInformationDetail" xlink:type="simple" xlink:href="tndm-20210630.xsd#BusinessSegmentandGeographicInformationAdditionalInformationDetail"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformationAdditionalInformationDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_55877a50-6774-49d5-b14c-893e8bc05b6b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_8e23597e-58cf-4c7e-b730-d4df3a43b421" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_55877a50-6774-49d5-b14c-893e8bc05b6b" xlink:to="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_8e23597e-58cf-4c7e-b730-d4df3a43b421" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_b9e3de4d-f110-46a7-ae2a-d6edb2e95038" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementGeographicalAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_8e23597e-58cf-4c7e-b730-d4df3a43b421" xlink:to="loc_srt_StatementGeographicalAxis_b9e3de4d-f110-46a7-ae2a-d6edb2e95038" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_7095da2c-06ed-477d-b6e6-d9924bc56812" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_SegmentGeographicalDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_b9e3de4d-f110-46a7-ae2a-d6edb2e95038" xlink:to="loc_srt_SegmentGeographicalDomain_7095da2c-06ed-477d-b6e6-d9924bc56812" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_US_0bd0d3a8-96b3-4e42-b071-d44b04f3d71e" xlink:href="https://xbrl.sec.gov/country/2021/country-2021.xsd#country_US"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_7095da2c-06ed-477d-b6e6-d9924bc56812" xlink:to="loc_country_US_0bd0d3a8-96b3-4e42-b071-d44b04f3d71e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_ab92faa8-1b6a-4c3d-a348-7e19b87bc370" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonUsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_7095da2c-06ed-477d-b6e6-d9924bc56812" xlink:to="loc_us-gaap_NonUsMember_ab92faa8-1b6a-4c3d-a348-7e19b87bc370" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_baccaec1-e3da-49da-876b-d3dd409ace4b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConcentrationRiskByBenchmarkAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_8e23597e-58cf-4c7e-b730-d4df3a43b421" xlink:to="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_baccaec1-e3da-49da-876b-d3dd409ace4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskBenchmarkDomain_b5592611-2289-425b-bdc3-4332d8482783" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConcentrationRiskBenchmarkDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByBenchmarkAxis_baccaec1-e3da-49da-876b-d3dd409ace4b" xlink:to="loc_us-gaap_ConcentrationRiskBenchmarkDomain_b5592611-2289-425b-bdc3-4332d8482783" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerMember_8e5018e5-5f1c-4917-aa90-21d478db9843" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskBenchmarkDomain_b5592611-2289-425b-bdc3-4332d8482783" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerMember_8e5018e5-5f1c-4917-aa90-21d478db9843" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskByTypeAxis_17d9e18d-8d7f-498c-9587-ec123a8aa5d8" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConcentrationRiskByTypeAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_8e23597e-58cf-4c7e-b730-d4df3a43b421" xlink:to="loc_us-gaap_ConcentrationRiskByTypeAxis_17d9e18d-8d7f-498c-9587-ec123a8aa5d8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskTypeDomain_1246ce9f-7281-48f1-8118-e9fbf6de3bdf" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConcentrationRiskTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskByTypeAxis_17d9e18d-8d7f-498c-9587-ec123a8aa5d8" xlink:to="loc_us-gaap_ConcentrationRiskTypeDomain_1246ce9f-7281-48f1-8118-e9fbf6de3bdf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CustomerConcentrationRiskMember_a4735b48-b241-43c7-a90b-c98bdeabf00d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CustomerConcentrationRiskMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ConcentrationRiskTypeDomain_1246ce9f-7281-48f1-8118-e9fbf6de3bdf" xlink:to="loc_us-gaap_CustomerConcentrationRiskMember_a4735b48-b241-43c7-a90b-c98bdeabf00d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_2fd8bf67-5e44-4c5b-b90a-347811d6a9cc" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_EntityWideRevenueMajorCustomerLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEntityWideRevenueByMajorCustomersByReportingSegmentsTable_8e23597e-58cf-4c7e-b730-d4df3a43b421" xlink:to="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_2fd8bf67-5e44-4c5b-b90a-347811d6a9cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_94975f48-19de-4ed8-a262-795f0a76649b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_2fd8bf67-5e44-4c5b-b90a-347811d6a9cc" xlink:to="loc_us-gaap_NumberOfOperatingSegments_94975f48-19de-4ed8-a262-795f0a76649b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConcentrationRiskPercentage1_aff35cdc-36ea-4793-a9f8-360f5d96fc19" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_ConcentrationRiskPercentage1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EntityWideRevenueMajorCustomerLineItems_2fd8bf67-5e44-4c5b-b90a-347811d6a9cc" xlink:to="loc_us-gaap_ConcentrationRiskPercentage1_aff35cdc-36ea-4793-a9f8-360f5d96fc19" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformationGeographicalMarketsDetail" xlink:type="simple" xlink:href="tndm-20210630.xsd#BusinessSegmentandGeographicInformationGeographicalMarketsDetail"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/BusinessSegmentandGeographicInformationGeographicalMarketsDetail" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_f746edd9-972f-4d8b-b6b2-0e2d3a4d7165" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueTable_a39f24f1-fc9c-4f5f-84bc-d7808a8684dd" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_f746edd9-972f-4d8b-b6b2-0e2d3a4d7165" xlink:to="loc_us-gaap_DisaggregationOfRevenueTable_a39f24f1-fc9c-4f5f-84bc-d7808a8684dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_705ae3ce-21e8-452e-86fd-73ac3357565b" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_StatementGeographicalAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_a39f24f1-fc9c-4f5f-84bc-d7808a8684dd" xlink:to="loc_srt_StatementGeographicalAxis_705ae3ce-21e8-452e-86fd-73ac3357565b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_b02b29ef-69af-4f30-b02c-09a2ac9f94ff" xlink:href="https://xbrl.fasb.org/srt/2021/elts/srt-2021-01-31.xsd#srt_SegmentGeographicalDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_705ae3ce-21e8-452e-86fd-73ac3357565b" xlink:to="loc_srt_SegmentGeographicalDomain_b02b29ef-69af-4f30-b02c-09a2ac9f94ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_US_f4e5750a-bb1c-4e09-ab2d-ed71dd0b8264" xlink:href="https://xbrl.sec.gov/country/2021/country-2021.xsd#country_US"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_b02b29ef-69af-4f30-b02c-09a2ac9f94ff" xlink:to="loc_country_US_f4e5750a-bb1c-4e09-ab2d-ed71dd0b8264" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_73320955-bab5-40ee-bb33-9077bac43086" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_NonUsMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_b02b29ef-69af-4f30-b02c-09a2ac9f94ff" xlink:to="loc_us-gaap_NonUsMember_73320955-bab5-40ee-bb33-9077bac43086" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DisaggregationOfRevenueLineItems_45243c39-0e5c-419e-bfa3-ca889c0e4f4d" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_DisaggregationOfRevenueLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueTable_a39f24f1-fc9c-4f5f-84bc-d7808a8684dd" xlink:to="loc_us-gaap_DisaggregationOfRevenueLineItems_45243c39-0e5c-419e-bfa3-ca889c0e4f4d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_a6c17a7a-cadb-4667-b3ee-d9ca567af043" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DisaggregationOfRevenueLineItems_45243c39-0e5c-419e-bfa3-ca889c0e4f4d" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_a6c17a7a-cadb-4667-b3ee-d9ca567af043" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="tndm-20210630.xsd#CommitmentsandContingencies"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CommitmentsandContingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_189e1732-e258-4eee-9603-d428f2dc5368" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_3a666963-e9e8-4138-9447-1f8916fa36b2" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_189e1732-e258-4eee-9603-d428f2dc5368" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_3a666963-e9e8-4138-9447-1f8916fa36b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.tandemdiabetes.com/role/CommitmentsandContingenciesAdditionalInformationDetails" xlink:type="simple" xlink:href="tndm-20210630.xsd#CommitmentsandContingenciesAdditionalInformationDetails"/>
  <link:presentationLink xlink:role="http://www.tandemdiabetes.com/role/CommitmentsandContingenciesAdditionalInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_ff1d4e2b-024e-458d-83a1-9822c0aff5fe" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyNewClaimsFiledNumber_260c8914-013a-468c-b19b-db3490bcfe0b" xlink:href="https://xbrl.fasb.org/us-gaap/2021/elts/us-gaap-2021-01-31.xsd#us-gaap_LossContingencyNewClaimsFiledNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_ff1d4e2b-024e-458d-83a1-9822c0aff5fe" xlink:to="loc_us-gaap_LossContingencyNewClaimsFiledNumber_260c8914-013a-468c-b19b-db3490bcfe0b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_tndm_NumberOfLegalProceedingsRegulatoryMattersOrOtherDisputesOrClaims_380f2192-fd03-410c-9d5e-6a3856cd47be" xlink:href="tndm-20210630.xsd#tndm_NumberOfLegalProceedingsRegulatoryMattersOrOtherDisputesOrClaims"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_ff1d4e2b-024e-458d-83a1-9822c0aff5fe" xlink:to="loc_tndm_NumberOfLegalProceedingsRegulatoryMattersOrOtherDisputesOrClaims_380f2192-fd03-410c-9d5e-6a3856cd47be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
